Ioannidis John P A, Gwinn Marta, Little Julian, Higgins Julian P T, Bernstein Jonine L, Boffetta Paolo, Bondy Melissa, Bray Molly S, Brenchley Paul E, Buffler Patricia A, Casas Juan Pablo, Chokkalingam Anand, Danesh John, Smith George Davey, Dolan Siobhan, Duncan Ross, Gruis Nelleke A, Hartge Patricia, Hashibe Mia, Hunter David J, Jarvelin Marjo-Riitta, Malmer Beatrice, Maraganore Demetrius M, Newton-Bishop Julia A, O'Brien Thomas R, Petersen Gloria, Riboli Elio, Salanti Georgia, Seminara Daniela, Smeeth Liam, Taioli Emanuela, Timpson Nic, Uitterlinden Andre G, Vineis Paolo, Wareham Nick, Winn Deborah M, Zimmern Ron, Khoury Muin J
Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, and Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina 45110, Greece.
Nat Genet. 2006 Jan;38(1):3-5. doi: 10.1038/ng0106-3.
Networks of investigators have begun sharing best practices, tools and methods for analysis of associations between genetic variation and common diseases. A Network of Investigator Networks has been set up to drive the process, sponsored by the Human Genome Epidemiology Network. A workshop is planned to develop consensus guidelines for reporting results of genetic association studies. Published literature databases will be integrated, and unpublished data, including 'negative' studies, will be captured by online journals and through investigator networks. Systematic reviews will be expanded to include more meta-analyses of individual-level data and prospective meta-analyses. Field synopses will offer regularly updated overviews.
研究人员网络已开始分享用于分析基因变异与常见疾病之间关联的最佳实践、工具和方法。由人类基因组流行病学网络赞助，已成立了一个研究人员网络联盟来推动这一进程。计划举办一次研讨会，以制定基因关联研究结果报告的共识指南。将整合已发表文献数据库，并通过在线期刊和研究人员网络获取未发表的数据，包括“阴性”研究。系统评价将扩大到包括更多个体水平数据的荟萃分析和前瞻性荟萃分析。领域综述将定期提供最新概述。
