Paraf A, Renault G, Rautureau J, Fabia F, Damour-Lebard J
Sem Hop. 1975 Mar 8;51(12):811-5.
The authors explored humoral and cellular immunity in 50 cases of alcoholic cirrhosis. The levels of the three serum immunoglobulins were greater than normal. IgM was significantly higher. The levels of antipolio antibodies (types I, II and III) were significantly higher in cirrhosis than in controls. The antistreptolysin and antistaphylolysin titers showed that the differences between levels found in cirrhosis and in controls were not significant. After taking the Sabin polio vaccine, variations in antipolio antibodies remained within normal limits, considering the high levels noted before taking the vaccine. Total serum complement was normal in 90% of the estimtions carried out. The results of the intradermal reactions were dissociated. Tuberculin skin tests were negative in 35% of cases of cirrhosis and in 14.3% of controls. In skin tests for candida and streptococcal antigen, differences between cirrhotics and controls were not significant. The absolute figure for blood lymphocytes per mm-3 was, in half the cases, less than normal.
作者对50例酒精性肝硬化患者的体液免疫和细胞免疫进行了研究。三种血清免疫球蛋白水平均高于正常。IgM显著升高。肝硬化患者中抗脊髓灰质炎抗体（I、II和III型）水平显著高于对照组。抗链球菌溶血素和抗葡萄球菌溶血素滴度显示，肝硬化患者与对照组的水平差异不显著。接种萨宾脊髓灰质炎疫苗后，鉴于接种疫苗前抗体水平较高，抗脊髓灰质炎抗体的变化仍在正常范围内。在90%的检测中，血清总补体正常。皮内反应结果不一致。35%的肝硬化病例和14.3%的对照组结核菌素皮肤试验呈阴性。在念珠菌和链球菌抗原皮肤试验中，肝硬化患者与对照组之间的差异不显著。每立方毫米血液淋巴细胞的绝对值在半数病例中低于正常水平。
