Monnet Eric, Pelsue Davyd, MacPhail Catriona
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Vet Surg. 2006 Feb;35(2):198-205. doi: 10.1111/j.1532-950X.2006.00132.x.
To validate laser doppler flowmetry (LDF) for measurement of blood flow in the stomach wall of dogs with gastric dilatation-volvulus (GDV).
Six purpose-bred dogs and 24 dogs with naturally occurring GDV.
Experimental and clinical.
Capillary blood flow in the body of the stomach and pyloric antrum was measured with LDF (tissue perfusion unit (TPU) before and after induction of portal hypertension (PH) and after PH plus gastric ischemia (GI; PH + GI) and compared with flow measured by colored microsphere technique. Capillary flow was measured by LDF in the stomach wall of dogs with GDV.
PH and PH+GI induced a significant reduction in blood flow in the body of the stomach (P = .019). A significant positive correlation was present between percent changes in capillary blood flow measured by LDF and colored microspheres after induction of PH + GI in the body of the stomach (r = 0.94, P = .014) and in the pyloric antrum (r = 0.95, P = .049). Capillary blood flow measured in the body of the stomach of 6 dogs that required partial gastrectomy (5.00+/-3.30 TPU) was significantly lower than in dogs that did not (28.00+/-14.40 TPU, P = .013).
LDF can detect variations in blood flow in the stomach wall of dogs.
LDF may have application for evaluation of stomach wall viability during surgery in dogs with GDV.
验证激光多普勒血流仪（LDF）用于测量胃扩张-扭转（GDV）犬胃壁血流的可行性。
6只专门培育的犬和24只自然发生GDV的犬。
实验性和临床性研究。
在门静脉高压（PH）诱导前后以及PH加胃缺血（GI；PH + GI）后，用LDF（组织灌注单位（TPU））测量胃体和幽门窦的毛细血管血流，并与彩色微球技术测量的血流进行比较。用LDF测量GDV犬胃壁的毛细血管血流。
PH和PH + GI导致胃体血流显著减少（P = .019）。在胃体诱导PH + GI后，LDF测量的毛细血管血流百分比变化与彩色微球测量的结果之间存在显著正相关（r = 0.94，P = .014），在幽门窦也存在显著正相关（r = 0.95，P = .049）。6只需要行部分胃切除术的犬胃体测量的毛细血管血流（5.00±3.30 TPU）显著低于未行部分胃切除术的犬（28.00±14.40 TPU，P = .013）。
LDF可检测犬胃壁血流变化。
LDF可能在GDV犬手术期间评估胃壁活力方面有应用价值。
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