Bensignor E, Grandemange E
Dermatology Referral Service, 6 rue Mare Pavée, 35510 Cesson Sévigné, France.
Vet Rec. 2006 Feb 11;158(6):193-5. doi: 10.1136/vr.158.6.193.
Twenty dogs with otitis externa in both ears and numerous Malassezia species yeasts on cytological examination were treated in one ear with a combination product containing clotrimazole, marbofloxacin and dexamethasone, and in the other ear with a topical antifungal containing miconazole. The effects of the treatments were analysed on the basis of the scores for pruritus, erythema and amount of cerumen, and the number of yeasts on cytological smears. There were reductions in the counts of Malassezia species after both treatments, but the combination product gave significantly greater reductions in erythema, cerumen and pruritus.
20只双耳患有外耳炎且在细胞学检查中发现大量马拉色菌属酵母菌的犬,一只耳朵用含有克霉唑、马波沙星和地塞米松的复方制剂治疗,另一只耳朵用含有咪康唑的局部抗真菌药治疗。根据瘙痒、红斑、耳垢量评分以及细胞学涂片上酵母菌数量对治疗效果进行分析。两种治疗后马拉色菌属的数量均有减少,但复方制剂在减轻红斑、耳垢和瘙痒方面的效果显著更佳。