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澳大利亚成年双胞胎队列中终生饮食失调的患病率及长期病程

Prevalence and long-term course of lifetime eating disorders in an adult Australian twin cohort.

作者信息

Wade Tracey D, Bergin Jacqueline L, Tiggemann Marika, Bulik Cynthia M, Fairburn Christopher G

机构信息

School of Psychology, Flinders University, Adelaide, South Australia, Australia.

出版信息

Aust N Z J Psychiatry. 2006 Feb;40(2):121-8. doi: 10.1080/j.1440-1614.2006.01758.x.

DOI:10.1080/j.1440-1614.2006.01758.x
PMID:16476129
Abstract

OBJECTIVE

Few studies exist that have examined the spectrum and natural long-term course of eating disturbance in the community. We examine the lifetime prevalence and long-term course of anorexia nervosa (AN), bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) in an adult female twin population.

METHOD

Female twins (n = 1002) from the Australian Twin Registry, aged 28-39 years, were assessed using the Eating Disorder Examination, revised to yield lifetime diagnostic information. For women with lifetime eating disorders, the assessment occurred, on average, 14.52 years (SD = 5.65) after onset of their disorder.

RESULTS

In accordance with other community studies, we found a 1.9% lifetime prevalence of AN, with an additional 2.4% who met the criteria for 'partial AN' (absence of amenorrhea). Criteria for BN were met by 2.9% of the women, an additional 2.9% of women met criteria for binge eating disorder, while 5.3% met criteria for purging disorder unaccompanied by binge eating (EDNOS-p). Eleven (7%) of the women with lifetime eating disorders had a current eating disorder. Each diagnostic group continued to be differentiated by current eating pathology from women without lifetime eating disorders. Although approximately 75% of the women had a good outcome, less than 50% of each diagnostic group was asymptomatic.

CONCLUSIONS

Eating disorders tend to improve over time often reaching subdiagnostic levels of severity, but only a minority of sufferers becomes asymptomatic. The DSM-IV diagnosis EDNOS needs to be considered in studies of the prevalence and course of eating disorders.

摘要

目的

很少有研究探讨社区中饮食失调的范围和自然长期病程。我们在成年女性双胞胎群体中研究神经性厌食症(AN)、神经性贪食症(BN)和未特定指明的饮食失调(EDNOS)的终生患病率和长期病程。

方法

对来自澳大利亚双胞胎登记处、年龄在28 - 39岁的女性双胞胎(n = 1002)进行评估,使用修订后的饮食失调检查来获取终生诊断信息。对于患有终生饮食失调的女性,评估平均在其疾病发作后14.52年(标准差 = 5.65)进行。

结果

与其他社区研究一致,我们发现AN的终生患病率为1.9%,另有2.4%符合“部分AN”标准(无闭经)。2.9%的女性符合BN标准,另有2.9%的女性符合暴饮暴食症标准,而5.3%符合无暴饮暴食的清除障碍标准(EDNOS - p)。11名(7%)患有终生饮食失调的女性目前患有饮食失调症。每个诊断组与没有终生饮食失调的女性相比,仍可通过当前的饮食病理状况进行区分。尽管约75%的女性预后良好,但每个诊断组中无症状的女性不到50%。

结论

饮食失调往往会随着时间改善,常常达到亚诊断水平的严重程度,但只有少数患者会无症状。在饮食失调患病率和病程的研究中需要考虑DSM - IV诊断的EDNOS。

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