Svedlund Nils Erik, Norring Claes, Ginsberg Ylva, von Hausswolff-Juhlin Yvonne
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Stockholm Centre for Eating Disorders, att: Nils Erik Svedlund, Wollmar Yxkullsgatan 27 B, 11850, Stockholm, Sweden.
BMC Psychiatry. 2017 Jan 17;17(1):19. doi: 10.1186/s12888-016-1093-1.
Very little is known about the prevalence of ADHD symptoms in Bulimia Nervosa and Binge Eating Disorder and even less in other eating disorders. This knowledge gap is of clinical importance since stimulant treatment is proven effective in Binge Eating Disorder and discussed as a treatment possibility for Bulimia Nervosa. The objective of this study was to explore the prevalence and types of self-reported ADHD symptoms in an unselected group of eating disorder patients assessed in a specialized eating disorder clinic.
In total 1165 adults with an eating disorder were assessed with a battery of standardized instruments, for measuring inter alia ADHD screening, demographic variables, eating disorder symptoms and psychiatric comorbidity. Chi-square tests were used for categorical variables and Kruskal-Wallis tests for continuous variables.
Almost one third (31.3 %) of the patients scored above the screening cut off indicating a possible ADHD. The highest prevalence rates (35-37 %) were found in Bulimia Nervosa and Anorexia Nervosa bingeing/purging subtype, while Eating Disorder Not Otherwise Specified type 1-4 and Binge Eating Disorder patients reported slightly below average (26-31 %), and Anorexia Nervosa restricting subtype patients even lower (18 %). Presence of binge eating, purging, loss of control over eating and non-anorectic BMI were related to results indicating a possible ADHD. Psychiatric comorbidity correlated to ADHD symptoms without explaining the differences between eating disorder diagnoses.
There is a high frequency of ADHD symptoms in patients with binge eating/purging eating disorders that motivates further studies, particularly concerning the effects of ADHD medication. The finding that the frequency of ADHD symptoms in anorexia nervosa with binge eating/purging is as high as in bulimia nervosa highlights the need also for this group.
关于神经性贪食症和暴食障碍中注意缺陷多动障碍(ADHD)症状的患病率知之甚少,而在其他饮食失调症中的了解更少。这一知识空白具有临床重要性,因为兴奋剂治疗已被证明对暴食障碍有效,并且被讨论作为神经性贪食症的一种治疗可能性。本研究的目的是在一家专门的饮食失调诊所评估的一组未经过筛选的饮食失调患者中,探索自我报告的ADHD症状的患病率和类型。
总共1165名患有饮食失调症的成年人接受了一系列标准化工具的评估,这些工具用于测量ADHD筛查、人口统计学变量、饮食失调症状和精神共病等。卡方检验用于分类变量,而Kruskal-Wallis检验用于连续变量。
近三分之一(31.3%)的患者得分高于筛查临界值,表明可能患有ADHD。在神经性贪食症和神经性厌食症的暴食/清除亚型中发现了最高患病率(35-37%),而未特定指明的饮食失调症1-4型和暴食障碍患者的报告略低于平均水平(26-31%),神经性厌食症限制亚型患者的患病率甚至更低(18%)。存在暴饮暴食、清除行为、饮食失控和非厌食性体重指数与表明可能患有ADHD的结果相关。精神共病与ADHD症状相关,但无法解释饮食失调诊断之间的差异。
在有暴饮暴食/清除行为的饮食失调患者中,ADHD症状的发生率很高,这促使进行进一步研究,特别是关于ADHD药物的效果。神经性厌食症暴食/清除型中ADHD症状的发生率与神经性贪食症一样高,这一发现也凸显了对这一群体进行研究的必要性。