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[坏血病:毛囊性紫癜作为一种诊断体征]

[Scurvy: follicular purpura as a diagnostic sign].

作者信息

Roé Esther, Dalmau Joan, Peramiquel Laura, Puig Lluis, Alomar Agustín

机构信息

Servicio de Dermatología, Hospital de Sant Pau, Barcelona, Spain.

出版信息

Actas Dermosifiliogr. 2005 Jul-Aug;96(6):400-2. doi: 10.1016/s0001-7310(05)73101-x.

DOI:10.1016/s0001-7310(05)73101-x
PMID:16476264
Abstract

Scurvy is a set of clinical manifestations characterized by general weakness, anemia, gingivitis and cutaneous bleeding, caused by a lack of ascorbic acid in the diet. This pathology is currently a clinical rarity, although it can still be seen in cases of malnutrition associated with alcoholism or with dietary deficiencies, especially in childhood and old age. We present the case of a 45-year-old male who consulted his physician because of lower limb edema with follicular purpura, accompanied by asthenia, polyarthralgia and bleeding gums. After treatment with 1 g/day of vitamin C was initiated, the patient's symptoms quickly improved. The diagnosis of scurvy was based on the patient's clinical symptoms, dietary history and the rapid resolution of the symptoms when vitamin C supplements were initiated.

摘要

坏血病是一组以全身乏力、贫血、牙龈炎和皮肤出血为特征的临床表现,由饮食中缺乏抗坏血酸引起。这种病症目前在临床上较为罕见,不过在与酗酒或饮食缺乏相关的营养不良病例中仍可见到,尤其是在儿童和老年人群中。我们报告一例45岁男性病例,该患者因下肢水肿伴毛囊性紫癜就诊,伴有乏力、多关节痛和牙龈出血。在开始每日服用1克维生素C进行治疗后,患者症状迅速改善。坏血病的诊断基于患者的临床症状、饮食史以及补充维生素C后症状迅速缓解。

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