Danilenko A M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(2):74-9.
Overall 467 male patients suffering from stage II and stage II-III chronic alcoholism were examined. Of these, 80 patients (17.1%) were with the abstinent syndrome, 66 (14.1%) had the abstinent convulsive syndrome, 251 (53.8%) were with alcoholic delirium and 80 (14.9%) making up a control group were in a state of remission. Noticeable disorders were revealed in enzymatic activity of the liver (hyperfermentemia) coupled with characteristic changes in proteolytic activity. The degree of disorders in enzymic function of the liver and of the proteolytic system correlates with the severity of the psychopathological syndrome, which suggests the existence of the common component underlying the development of the pathogenetic mechanism in abstinent patients and in those with alcoholic delirium. The alcoholic abstinent syndrome and delirium are stages of the common pathological process.
对467例患有II期和II - III期慢性酒精中毒的男性患者进行了检查。其中，80例患者（17.1%）出现戒断综合征，66例（14.1%）患有戒断惊厥综合征，251例（53.8%）出现酒精性谵妄，80例（14.9%）作为对照组处于缓解状态。研究发现肝脏酶活性（高酶血症）出现明显紊乱，并伴有蛋白水解活性的特征性变化。肝脏酶功能和蛋白水解系统的紊乱程度与精神病理综合征的严重程度相关，这表明在戒断患者和酒精性谵妄患者发病机制的发展中存在共同的潜在因素。酒精戒断综合征和谵妄是同一病理过程的不同阶段。
