Sigüenza Mercedes, Pizarro Angel, Mayor Matías, Vidaurrázaga Carmen, Miralles Lara, González-Beato María, Casado Mariano
Servicios de Dermatología, Hospital Universitario La Paz, Valle de Bergantiños 23, B-B, 28039 Madrid, Spain.
Actas Dermosifiliogr. 2005 Mar;96(2):111-5. doi: 10.1016/s0001-7310(05)73048-9.
The treatment of skin metastases of melanoma can be difficult in many cases because of the patients age, as well as the number, size and location of the lesions. We present the case of an 82-year-old male with melanoma skin metastases on the scalp, which responded satisfactorily to treatment with 5 % imiquimod cream. Imiquimod is a topical immunomodulator with antiviral and antineoplastic action. This case, along with others that have recently been published, supports the usefulness of this treatment in selected cases of melanoma skin metastases, at least for palliative purposes.
由于患者年龄以及皮损的数量、大小和位置等因素，黑色素瘤皮肤转移瘤的治疗在很多情况下可能会很困难。我们报告一例82岁男性患者，其头皮出现黑色素瘤皮肤转移瘤，使用5%咪喹莫特乳膏治疗后反应良好。咪喹莫特是一种具有抗病毒和抗肿瘤作用的局部免疫调节剂。该病例以及最近发表的其他病例均支持这种治疗方法在某些黑色素瘤皮肤转移瘤病例中的有效性，至少可用于姑息治疗目的。
