局部使用咪喹莫特可清除侵袭性黑色素瘤。
Topical imiquimod clears invasive melanoma.
作者信息
Grady Brittany E, Spencer James M
机构信息
DeBusk College of Osteopathic Medicine, Lincoln Memorial University, Harrogate, Tennessee, USA.
Icahn School of Medicine at Mount Sinai, New York, New York, and private practice, St. Petersburg, Florida, USA.
出版信息
Cutis. 2016 Nov;98(5):E28-E30.
Malignant melanoma has continually shown a pattern of increased incidence and mortality in the last 50 years. Currently, wide local excision is the mainstay of treatment of primary cutaneous melanomas. Imiquimod has been shown to clear cases of melanoma in situ, but its role in the treatment of invasive cutaneous melanomas is unknown. We present the case of a patient who achieved complete histologic clearance of invasive melanoma following treatment with topical imiquimod.
在过去50年中，恶性黑色素瘤的发病率和死亡率持续呈上升趋势。目前，广泛局部切除是原发性皮肤黑色素瘤的主要治疗方法。咪喹莫特已被证明可清除原位黑色素瘤病例，但其在侵袭性皮肤黑色素瘤治疗中的作用尚不清楚。我们报告了一例患者，其在接受局部咪喹莫特治疗后，侵袭性黑色素瘤实现了组织学完全清除。
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