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Acute administration of carnitine to rats modified the basal and A23187-stimulated release of eicosanoids from 4 day carrageenin-elicited peritoneal macrophages.

作者信息

Elliott G R, Lauwen A P, Bonta I L

机构信息

Pharmacology Department, Medical Biological Laboratory, TNO, The Netherlands.

出版信息

Agents Actions. 1991 Jan;32(1-2):88-9. doi: 10.1007/BF01983322.

DOI:10.1007/BF01983322
PMID:1647652
Abstract
摘要

相似文献

1
Acute administration of carnitine to rats modified the basal and A23187-stimulated release of eicosanoids from 4 day carrageenin-elicited peritoneal macrophages.给大鼠急性注射肉碱，可改变角叉菜胶诱导4天的腹膜巨噬细胞中类二十烷酸的基础释放及A23187刺激的释放。
Agents Actions. 1991 Jan;32(1-2):88-9. doi: 10.1007/BF01983322.
2
The effect of acute feeding of carnitine, acetyl carnitine and propionyl carnitine on basal and A23187-stimulated eicosanoid release from rat carrageenan-elicited peritoneal macrophages.
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3
Local and systemic effects of an acute inflammation on eicosanoid generation capacity of polymorphonuclear cells and macrophages.急性炎症对多形核细胞和巨噬细胞类花生酸生成能力的局部和全身影响。
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Dibutyryl cytidine 3':5'-cyclic monophosphate; an inhibitor of A23187-stimulated macrophage leukotriene B4 synthesis.
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Prostaglandin E2 inhibits and indomethacin and aspirin enhance, A23187-stimulated leukotriene B4 synthesis by rat peritoneal macrophages.前列腺素E2抑制，而消炎痛和阿司匹林增强A23187刺激的大鼠腹腔巨噬细胞白三烯B4的合成。
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Altered release of eicosanoids by rat alveolar macrophages during granulomatous pulmonary inflammation.肉芽肿性肺部炎症期间大鼠肺泡巨噬细胞类花生酸释放的改变
Am J Respir Cell Mol Biol. 1990 Mar;2(3):289-96. doi: 10.1165/ajrcmb/2.3.289.
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Effects of short- and long-term feeding of L-carnitine and congeners on the production of eicosanoids from rat peritoneal leucocytes.
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Alterations in eicosanoid production by rat alveolar type II cells isolated after silica-induced lung injury.二氧化硅诱导的肺损伤后分离的大鼠II型肺泡细胞中类花生酸生成的变化。
Am J Respir Cell Mol Biol. 1992 Apr;6(4):430-8. doi: 10.1165/ajrcmb/6.4.430.
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Endotoxin-induced procoagulant activity, eicosanoid synthesis, and tumor necrosis factor production by rat peritoneal macrophages: effect of endotoxin tolerance and glucan.内毒素诱导大鼠腹腔巨噬细胞的促凝血活性、类花生酸合成及肿瘤坏死因子产生：内毒素耐受和葡聚糖的影响
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Calcium-ionophore A23187 induces dual changes in the release of 5-lipoxygenase and cyclooxygenase products by macrophages.钙离子载体A23187可诱导巨噬细胞释放5-脂氧合酶和环氧化酶产物发生双重变化。
Arch Int Pharmacodyn Ther. 1990 Mar-Apr;304:55-63.

本文引用的文献

1
Arachidonic acid synthesis in isolated liver cells:" effects of (-)-carnitine and of (+)-decanoylcarnitine.
FEBS Lett. 1981 Oct 26;133(2):201-4. doi: 10.1016/0014-5793(81)80505-4.
2
Reactive oxygen production associated with arachidonic acid metabolism by peritoneal macrophages.腹膜巨噬细胞花生四烯酸代谢相关的活性氧生成
Biochem Biophys Res Commun. 1980 Dec 16;97(3):973-80. doi: 10.1016/0006-291x(80)91472-2.
3
Carnitine--metabolism and functions.肉碱——代谢与功能
Physiol Rev. 1983 Oct;63(4):1420-80. doi: 10.1152/physrev.1983.63.4.1420.
4
Cyclooxygenase inhibitors promote the leukotriene C4 induced release of beta-glucuronidase from rat peritoneal macrophages: prostaglandin E2 suppresses.
Int J Immunopharmacol. 1986;8(3):305-11. doi: 10.1016/0192-0561(86)90112-8.
5
Effect of l-carnitine on human neutrophil activity.左旋肉碱对人中性粒细胞活性的影响。
Int J Tissue React. 1986;8(3):199-203.
6
Prostacyclin and thromboxane A2 biosynthesis capacities of heart, arteries and platelets at various stages of experimental atherosclerosis in rabbits.
Atherosclerosis. 1978 Dec;31(4):385-94. doi: 10.1016/0021-9150(78)90133-8.