Saltzman Kasey M, Weems Carl F, Reiss Allan L, Carrión Victor G
Stanford University School of Medicine, Stanford, CA 94305, USA.
J Nerv Ment Dis. 2006 Feb;194(2):142-4. doi: 10.1097/01.nmd.0000198201.59824.37.
Recent research indicates that adults with posttraumatic stress disorder (PTSD) have a higher incidence of mixed laterality with respect to handedness than the rest of the population. To test if this relationship also occurs early in life, we evaluated children with history of interpersonal trauma. Fifty-nine traumatized children were evaluated with the Clinician Administered PTSD Scale for Children and Adolescents and the Edinburgh Handedness Inventory. Forty matched healthy controls were used for comparison. Increased mixed laterality was found in all children exhibiting symptoms of PTSD when compared with healthy controls, and children who met DSM-IV diagnostic criteria for PTSD had more mixed laterality than the subthreshold traumatized group (F = 7.71; df = 2,96; p = 0.001). Within the entire traumatized group, there was a positive correlation between PTSD symptom severity and mixed laterality. Mixed laterality was positively associated with PTSD symptoms in traumatized children, suggesting that neurological abnormalities may be related to degree of PTSD symptom expression.
近期研究表明，患有创伤后应激障碍（PTSD）的成年人在利手方面出现混合利手的发生率高于其他人群。为了测试这种关系是否也在生命早期出现，我们评估了有人际创伤史的儿童。59名受创伤儿童接受了儿童和青少年临床医师管理的PTSD量表以及爱丁堡利手问卷的评估。选取40名匹配的健康对照儿童进行比较。与健康对照儿童相比，所有表现出PTSD症状的儿童都出现了混合利手增加的情况，并且符合DSM-IV PTSD诊断标准的儿童比未达阈值的受创伤组儿童有更多的混合利手（F = 7.71；自由度 = 2,96；p = 0.001）。在整个受创伤组中，PTSD症状严重程度与混合利手之间存在正相关。混合利手与受创伤儿童的PTSD症状呈正相关，这表明神经学异常可能与PTSD症状表达程度有关。
