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长期机构照料中老年人使用抗精神病药物情况:三年随访

Use of antipsychotic medications among elderly residents in long-term institutional care: a three-year follow-up.

作者信息

Alanen Hanna-Mari, Finne-Soveri Harriet, Noro Anja, Leinonen Esa

机构信息

University of Tampere, Medical School, University of Tampere, Finland.

出版信息

Int J Geriatr Psychiatry. 2006 Mar;21(3):288-95. doi: 10.1002/gps.1462.

Abstract

OBJECTIVE

To analyse the use of antipsychotic medications, change over time and associated factors in a three-year follow-up among elderly residents in long-term institutional care.

DESIGN

Retrospective study was designed with three identical cross-sectional samples originating from the same long-term care facilities, and collected 1 July to 31 December in 2001, 2002 and 2003, in Finland. These were extracted from the Resident Assessment Instrument (RAI) database, based on Minimum Data Set (MDS) assessments.

SETTING

Of the data providers 16 were hospital-based institutions and 25 residential homes.

PARTICIPANTS

Each of the data sets included 3,662-3,867 resident assessments.

RESULTS

The prevalence use of one or more antipsychotic decreased from 42% in 2001 to 39% in 2003. The overall confounder-adjusted decrease in antipsychotic use was not statistically significant. However, the use of antipsychotics decreased among residents who had wandering as a behavioural problem (OR 0.79, 95% CI 0.63-0.99) and increased among residents with concomitant use of anxiolytic medications (OR 1.23, 95% CI 1.03-1.48).

CONCLUSIONS

The use of antipsychotic medications among residents in long-term institutional care was common and the caring patterns were quite stable during the observation period. Adequate indications may not have been achieved in all cases. More attention should be paid to the appropriate use of antipsychotics in this frail population.

摘要

目的

分析长期机构照料的老年居民在三年随访期间抗精神病药物的使用情况、随时间的变化及相关因素。

设计

采用回顾性研究,样本来自芬兰同一长期护理机构的三个相同横断面样本,分别于2001年、2002年和2003年的7月1日至12月31日收集。这些数据基于最低数据集(MDS)评估,从居民评估工具(RAI)数据库中提取。

设置

数据提供者包括16家医院机构和25家养老院。

参与者

每个数据集包含3662 - 3867名居民评估。

结果

使用一种或多种抗精神病药物的患病率从2001年的42%降至2003年的39%。抗精神病药物使用的总体混杂因素调整后下降无统计学意义。然而,有徘徊行为问题的居民中抗精神病药物的使用减少(比值比0.79,95%置信区间0.63 - 0.99),同时使用抗焦虑药物的居民中抗精神病药物的使用增加(比值比1.23,95%置信区间1.03 - 1.48)。

结论

长期机构照料居民中抗精神病药物的使用很常见,且在观察期内护理模式相当稳定。并非所有病例都有充分的用药指征。应更加关注在这一脆弱人群中抗精神病药物的合理使用。

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