西孟加拉邦北孟加拉医学院收治儿童急性脑病毒感染的临床流行病学研究

A clinico epidemiological study on acute viral infection of brain among children admitted in North Bengal Medical College, West Bengal.

作者信息

Das P K, Sarkar G N, Basu K, Paul D, Lahiri S

机构信息

Dr. B. C. Roy Memorial Hospital for Children, Kolkata.

出版信息

Indian J Public Health. 2005 Oct-Dec;49(4):260-2.

PMID:16479917

Abstract

A clinico epidemiological prospective study was carried out on acute viral infection of brain among children admitted in a rural based medical college from September '99 to Oct '01. Out of 80 cases, 8 cases (10%) of aseptic meningitis, 35 cases (43.75%) of encephalitis and 37 cases (6.25%) of meningo-encephalitis were found. Overall case fatality was 47.5% and found higher (77%) among normally nourished children in comparison to malnourished children (47.5%). Virological investigation did not isolate any known Flavivirus, Herpes Simplex virus (HSV) and Measles virus; nor any serological evidence against these viruses.

摘要

1999年9月至2001年10月期间，在一所农村医学院收治的儿童中，对急性脑病毒感染进行了一项临床流行病学前瞻性研究。在80例病例中，发现8例（10%）无菌性脑膜炎、35例（43.75%）脑炎和37例（6.25%）脑膜脑炎。总体病死率为47.5%，发现营养正常儿童的病死率（77%）高于营养不良儿童（47.5%）。病毒学调查未分离出任何已知的黄病毒、单纯疱疹病毒（HSV）和麻疹病毒；也没有针对这些病毒的血清学证据。