小脑内粒细胞肉瘤。病例报告。
Intracerebellar granulocytic sarcoma. A case report.
作者信息
Chelly I, Mekni A, Kchir N, Karim B H, Khadija B, Selma B, Slim H, Khaldi M, Zitouna M
机构信息
Department of Pathology, Hospital La Rabta, 1007 Bab Saadoun, Tunis, Tunisia.
出版信息
Pathologica. 2005 Oct;97(5):335-7.
Granulocytic sarcoma is a form of extramedullary leukaemia. The intraparenchymal localisation is extremely rare. We report a case of cerebellar granulocytic sarcoma occuring in a 43 years old woman without any precedent medical history. The diagnosis of granulocytic sarcoma was established by neoplastic cells findings through morphological and immunohistochemical studies. The patient died few days after surgery. There are still no conclusive treatment strategies for this entity; however, early antileukemic chemotherapy seems to lower the probability of developing systemic disease and thus prolong survival.
粒细胞肉瘤是髓外白血病的一种形式。实质内定位极为罕见。我们报告一例发生在一名43岁无既往病史女性的小脑粒细胞肉瘤病例。通过形态学和免疫组织化学研究发现肿瘤细胞，从而确立了粒细胞肉瘤的诊断。患者术后几天死亡。对于该实体疾病仍没有确凿的治疗策略；然而，早期抗白血病化疗似乎能降低发生全身性疾病的概率，从而延长生存期。
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