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唇部粒细胞肉瘤:一例罕见病例报告。

Granulocytic sarcoma of the lips: report of an unusual case.

作者信息

Srinivasan Badri, Ethunandan Madanagopal, Anand Rajiv, Hussein Kudair, Ilankovan Velupillai

机构信息

Department of Maxillofacial Surgery, Poole Hospital NHS Trust, Dorset, UK.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jan;105(1):e34-6. doi: 10.1016/j.tripleo.2007.07.020.

Abstract

Granulocytic sarcoma (GS) is a rare localized, extramedullary tumor composed of immature cells of granulocyte series. It is capable of marked local tissue destruction. This condition can be a precursor of acute myeloid leukaemia by months or years making its diagnosis critical. Its occurrence has been described in multiple sites including skin, lymph nodes, bone, and visceral organs. It is extremely rare in the oral cavity and only 30 cases have been reported in the literature to date and often as a lump in the gingiva, palate, and extraction sockets. We describe the first reported case of GS presenting as a solitary lump in the lip and review the pertinent literature.

摘要

粒细胞肉瘤(GS)是一种罕见的局限性髓外肿瘤,由粒细胞系列的未成熟细胞组成。它能够造成显著的局部组织破坏。这种情况可能在数月或数年之后成为急性髓系白血病的先兆,因此其诊断至关重要。它已被报道出现在多个部位,包括皮肤、淋巴结、骨骼和内脏器官。在口腔中极为罕见,迄今为止文献中仅报道了30例,且通常表现为牙龈、腭部和拔牙窝处的肿块。我们描述了首例报道的以唇部孤立肿块形式出现的GS病例,并对相关文献进行了综述。

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