Dutta S K, Shipley W D
Am J Vet Res. 1975 Apr;36(4 Pt.1):445-8.
Foals (farms 1 and 2) and mares (farms 1 and 3) vaccinated with a commercially available rhinopneumonitis vaccine were tested for the level of antibodies and for protection against the natural infection. The serum-neutralization (SN) antibody titers against equine herpesvirus type 1 were 1:8 or less in the majority of foals and 1:16 or higher in about 10%. The level of the nasal secretory antibody in the foals (farm 2) was less than 1:4. The vaccinated foals did not show any apparent respiratory tract infection for about 6 months and then an epizootic of respiratory tract disease appeared on farm 1 involving 3 foals. From each of these 3 foals herpesvirus was isolated. On farm 1, about 50% of the vaccinated mares aborted, and on farm 3, there were no abortions. Isolations of herpesvirus were made from 5 of the 6 aborted fetuses (farm 1). The SN antibody titers of the pregnant mares in the 2 farms at the time of foaling were high.
用市售鼻肺炎疫苗接种的马驹（农场1和2）和母马（农场1和3）进行了抗体水平检测以及针对自然感染的保护性检测。大多数马驹针对1型马疱疹病毒的血清中和（SN）抗体效价为1:8或更低，约10%的马驹抗体效价为1:16或更高。马驹（农场2）鼻分泌抗体水平低于1:4。接种疫苗的马驹在约6个月内未出现任何明显的呼吸道感染，之后农场1出现了一起呼吸道疾病流行，涉及3匹小马驹。从这3匹小马驹中均分离出了疱疹病毒。在农场1，约50%接种疫苗的母马发生流产，而在农场3，没有流产情况。从6例流产胎儿中的5例（农场1）分离出了疱疹病毒。两个农场的怀孕母马在产驹时SN抗体效价都很高。
