Bhattacharyya Neil
Division of Otolaryngology, Brigham and Women's Hospital, Division of Otology & Laryngology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Laryngoscope. 2006 Jan;116(1):18-22. doi: 10.1097/01.mlg.0000192284.22703.04.
To determine whether preoperative computed tomography (CT) stage predicts degree of symptom improvement after endoscopic sinus surgery (ESS).
A series of adult patients undergoing ESS was prospectively evaluated with CT and the rhinosinusitis symptom inventory (RSI) preoperatively and at a minimum of 12 months postoperatively. Symptom domains (nasal, facial, oropharyngeal, systemic, and total) were computed and both absolute change and percentage change in symptom domain scores before and after ESS were correlated with the preoperative CT scan stage according to three staging systems: Lund-MacKay, Kennedy, and Harvard.
One-hundred sixty-one patients (mean age, 40.2 years) completed the study with a mean follow-up of 19.4 months. Overall, statistically significant decreases in RSI symptom domains were noted for the nasal (net change -30.1 [range -100 to +100]), facial (-26.1), oropharyngeal (-13.4), systemic (-17.0), and total (-20.8) symptom scores (all P < .001). For the absolute change in total symptom score, no statistically significant correlation with CT stage was demonstrated for any of the staging systems (Lund: Spearman rho = -0.004, P = .962; Kennedy: rho = -0.008, P = .918; Harvard: rho = -0.011, P= .891). Similarly, no significant correlation with CT stage was demonstrated with the other symptom domains. Additionally, no significant correlation was identified between preoperative CT stage and percentage change in symptom domain scores.
Although CT scan is widely accepted as an accurate diagnostic tool for chronic rhinosinusitis, CT scan stage alone does not significantly predict symptom outcomes after chronic rhinosinusitis, regardless of staging system utilized.
确定术前计算机断层扫描(CT)分期能否预测内镜鼻窦手术(ESS)后症状改善程度。
对一系列接受ESS的成年患者进行前瞻性评估,术前及术后至少12个月时进行CT和鼻窦炎症状量表(RSI)评估。计算症状域(鼻腔、面部、口咽、全身及总分),并根据Lund-MacKay、Kennedy和哈佛三种分期系统,将ESS前后症状域得分的绝对变化和百分比变化与术前CT扫描分期进行相关性分析。
161例患者(平均年龄40.2岁)完成研究,平均随访19.4个月。总体而言,RSI症状域得分在鼻腔(净变化-30.1[范围-100至+100])、面部(-26.1)、口咽(-13.4)、全身(-17.0)及总分(-20.8)均有统计学意义的显著下降(均P<.001)。对于总症状得分的绝对变化,任何分期系统均未显示与CT分期有统计学意义的相关性(Lund:Spearman秩相关系数=-0.004,P=.962;Kennedy:rho=-0.008,P=.918;哈佛:rho=-0.011,P=.891)。同样地,其他症状域与CT分期也未显示显著相关性。此外,术前CT分期与症状域得分的百分比变化之间也未发现显著相关性。
尽管CT扫描被广泛认为是慢性鼻窦炎的准确诊断工具,但无论采用何种分期系统,单纯的CT扫描分期并不能显著预测慢性鼻窦炎手术后的症状转归。