Caylakli Fatma, Yavuz Haluk, Erkan Alper Nabi, Ozer Cem, Ozluoglu Levent Naci
Department of Otorhinolaryngology Head and Neck Surgery, Baskent University Faculty of Medicine, Adana Teaching and Research Medical Center, Turkey.
Laryngoscope. 2006 Jan;116(1):37-9. doi: 10.1097/01.mlg.0000191457.78244.96.
The objective of this study was to determine the value of barium swallow pharyngoesophagography in the investigation of patients with globus pharyngeus who had no known disease, no operation history in the head and neck region, and no thyroid pathology. We compare the clinical presentation with the radiologic findings to assess the diagnostic accuracy of barium swallow in such patients.
This was a retrospective study of the clinical records and radiologic reports of 194 patients with globus pharyngeus, between October 1998 and October 2004, that were reviewed and analyzed for correlations between clinical signs and symptoms and barium swallow findings using the chi2 test. All the patients had normal ear, nose, and throat examination, including indirect laryngoscopy and/or nasoendoscopy. Patients with known pharyngeal and esophageal disease, neurologic disease known to cause pharyngeal or esophageal dysfunction, evidence of autoimmune disease or diabetes mellitus, with a thyroid operation in the past and thyroid nodules detected with radiologic investigation were excluded.
There were 116 (59.8%) female and 78 (40.2%) male patients. In 114 patients (59%), globus was the only symptom. Sore throat was the most common associated complaint. Benign barium swallow findings were detected in 63.9% of the patients. Cervical osteophyte indentation was the most common finding. In 36.1% of the patients, the radiologic finding was normal. The statistical analysis using the chi2 test showed a significant relationship (P < .001) between the symptoms of globus pharyngeus and the barium swallow results.
Barium swallow pharyngoesophagography is useful to detect underlying benign characteristic pathologies in patients with globus who have no known head and neck illness.
本研究的目的是确定吞咽钡剂咽食管造影在检查咽部异物感患者中的价值，这些患者无已知疾病、无头颈部手术史且无甲状腺病变。我们将临床表现与放射学检查结果进行比较，以评估吞咽钡剂在这类患者中的诊断准确性。
这是一项对194例咽部异物感患者的临床记录和放射学报告的回顾性研究，研究时间为1998年10月至2004年10月，使用卡方检验对临床体征和症状与吞咽钡剂检查结果之间的相关性进行回顾和分析。所有患者的耳鼻喉检查均正常，包括间接喉镜检查和/或鼻内镜检查。排除已知有咽和食管疾病、已知会导致咽或食管功能障碍的神经疾病、自身免疫性疾病或糖尿病证据、既往有甲状腺手术史以及放射学检查发现甲状腺结节的患者。
有116例（59.8%）女性患者和78例（40.2%）男性患者。114例患者（59%）中，咽部异物感是唯一症状。咽痛是最常见的伴随主诉。63.9%的患者吞咽钡剂检查结果为良性。颈椎骨质增生压迫是最常见的发现。36.1%的患者放射学检查结果正常。使用卡方检验的统计分析显示，咽部异物感症状与吞咽钡剂检查结果之间存在显著相关性（P < .001）。
吞咽钡剂咽食管造影有助于检测无已知头颈部疾病的咽部异物感患者潜在的良性特征性病变。
