Grigor'ian A S, Grigor'iants L A, Kasparov A S
Stomatologiia (Mosk). 2006;85(1):8-13.
An experimental-morphologic study of the effects of diode laser scalpel with different irradiation parameters (wave length 0.97 mm) on oral mucosa of 12 rabbits showed that incisions on oral membrane of the tongue, cheek and palate made by diode laser scalpel in different modes of operation (diode laser scalpel LC-0.97-IRE-Polus: in continuous mode /4 W/; frequency modulated mode 2000 x 100 /5 W/; frequency modulated mode 1000 x 50 /6 W/) after 2 hours produced the effect of superficial tissues defects with consequent development in 1-2 days of necrotic changes, oedema and angiomatosis, as well as perifocal inflammatory and productive reactions in the defects walls. In the continuous mode /4 W/ and frequency modulated mode 2000 x 100 /5 W/ to 10th day of the experiment there was epithelization of mucous defects on thr tongue, cheek and palate. This effect was observed only on day 20 after the frequency modulated mode 1000 x 50 /6 W/. In the control (incisions by radio-wave scalpel) epithelization of oral mucous membrane defects was seen on day 5-10 that was comparable with laser scalpel effects. Thus optimal results (by criterion of oral mucous membrane incisions healing) were received in the continuous mode /4 W/ and frequency modulated mode 2000 x 100 /5 W/.
一项关于不同照射参数（波长0.97毫米）的二极管激光手术刀对12只兔子口腔黏膜影响的实验形态学研究表明，二极管激光手术刀在不同操作模式下（二极管激光手术刀LC - 0.97 - IRE - Polus：连续模式/4瓦/；调频模式2000×100/5瓦/；调频模式1000×50/6瓦/）对舌、颊和腭的口腔黏膜进行切割后，2小时产生浅表组织缺损效应，随后在1 - 2天出现坏死变化、水肿和血管瘤形成，以及缺损壁周围的局灶性炎症和增生反应。在连续模式/4瓦/和调频模式2000×100/5瓦/下，到实验第10天，舌、颊和腭的黏膜缺损出现上皮化。这种效应仅在调频模式1000×50/6瓦/后的第20天观察到。在对照组（用无线电波手术刀切割）中，口腔黏膜缺损在第5 - 10天出现上皮化，这与激光手术刀的效果相当。因此，在连续模式/4瓦/和调频模式2000×100/5瓦/下获得了最佳结果（以口腔黏膜切口愈合为标准）。
