Smets K, Salgado R, Simons P J, De Clercq R, De Smedt K, Cras P
Department of Neurology, Sint-Vincentius Hospital, Antwerp, Belgium.
Acta Neurol Belg. 2005 Dec;105(4):218-25.
We report a case of a 25 year old man presenting with acute headache, vomiting and nuchal rigidity. Computed Tomography (CT) scan and MRI without contrast showed a right ventricular hemorrhage surrounding a mass lesion. The tumor and hematoma were completely removed by neurosurgical transcortical-transventricular approach. Anatomopathological analysis revealed a central neurocytoma. Central neurocytoma seldom present with hemorrhage. We review 16 cases of neurocytoma with hemorrhage. It is important to recognize central neurocytoma as a cause of intraventricular hemorrhage, especially in adolescents and young adults. Outcome is often favorable when the tumor is completely removed. In some patients the clinical course is more aggressive and additional treatment such as radiotherapy, radiosurgery or chemotherapy is needed.
我们报告一例25岁男性患者,表现为急性头痛、呕吐和颈项强直。计算机断层扫描(CT)和无对比剂的磁共振成像(MRI)显示右心室出血,周围有一肿块病变。通过神经外科经皮质-经心室入路将肿瘤和血肿完全切除。解剖病理学分析显示为中枢神经细胞瘤。中枢神经细胞瘤很少伴有出血。我们回顾了16例伴有出血的神经细胞瘤病例。认识到中枢神经细胞瘤是脑室内出血的一个原因很重要,尤其是在青少年和年轻成年人中。当肿瘤完全切除时,预后通常良好。在一些患者中,临床病程更具侵袭性,需要额外的治疗,如放疗、放射外科或化疗。