Salinas Sánchez A S, Alcalá-Santaella Casanova C, Martínez Martín M, Pastor Guzmán J M, Cañamares Pabolaza L, Virseda Rodríguez J
Servicio de Urología, Hospital General de Albacete, España.
Arch Esp Urol. 1991 Jan-Feb;44(1):31-6.
Tumors of the urachus account for 1% of all malignant bladder tumors and 20-39% of primary adenocarcinoma of the bladder. We report 4 cases (3 males, 1 female) of urachal adenocarcinoma. One of the patients had a signet ring cell tumor. The most common clinical sign was a suprapubic mass followed by hematuria. In three cases, cystoscopy revealed a mass at the level of the bladder dome. The IVP was normal in all but one patient in whom a filling defect at the level of the dome was evidenced by the cystogram. In one patient, CT revealed a fistulous track between the bladder and the tumor mass. Treatment was by surgery in all of the cases. Supratrigonal cystectomy and en bloc resection of the anterior infraumbilical abdominal wall was performed in 3 cases, followed by wide cystoplasty using intestine in 2 cases. One patient underwent radical cystectomy and Bricker urinary diversion. Two patients are alive and disease-free at 2 and 10 years, respectively. The other two patients have died; one following operation for high gastrointestinal hemorrhage, and the other at two years from generalized metastasis. The clinical findings reported in the literature, the diagnostic protocols and treatment of these tumor types are discussed.
脐尿管肿瘤占所有膀胱恶性肿瘤的1%,占膀胱原发性腺癌的20 - 39%。我们报告4例(3例男性,1例女性)脐尿管腺癌。其中1例患者为印戒细胞肿瘤。最常见的临床症状是耻骨上肿块,其次是血尿。3例患者经膀胱镜检查发现膀胱顶部有肿块。除1例患者外,其余患者静脉肾盂造影(IVP)均正常,该例患者经膀胱造影显示顶部有充盈缺损。1例患者CT显示膀胱与肿瘤肿块之间有瘘管。所有病例均采用手术治疗。3例行膀胱三角区上方膀胱切除术及脐下前腹壁整块切除术,其中2例随后采用肠道进行广泛膀胱成形术。1例患者接受了根治性膀胱切除术及Bricker尿流改道术。2例患者分别在术后2年和10年存活且无疾病。另外2例患者死亡;1例因上消化道大出血手术后死亡,另1例在两年后因全身转移死亡。本文讨论了文献中报道的这些肿瘤类型的临床发现、诊断方案及治疗方法。