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[治疗方法作为8例脐尿管癌患者的预后因素]

[Treatment methods as a prognostic factor in eight patients with urachal carcinoma].

作者信息

Yamada T, Fukui I, Sekine H, Kihara K, Oshima H

机构信息

Department of Urology, Tokyo Medical and Dental University School of Medicine.

出版信息

Hinyokika Kiyo. 1991 Feb;37(2):113-6.

PMID:2048489
Abstract

Between 1960 and 1982, 8 patients with urachal carcinoma underwent segmental resection of the bladder or en bloc resection, and their five-year survival rate was 50%. One patient each with well, moderate and poorly differentiated adenocarcinoma and one patient with transitional cell carcinoma, died of cancer from 6 months to 2 years and 2 months after operation (mean duration: 1 year and 3 months). The patient with well differentiated adenocarcinoma underwent en bloc resection and was recognized to have peritoneal involvement of the tumor at the operation. The remaining three patients were diagnosed to have tumors confined to their bladder and urachal remnant and were treated with segmental resection of the bladder. Two patients each, with well and moderately differentiated carcinoma confined to their bladder and urachal remnant, were treated with en bloc resection and have been surviving from 8 years and 5 months to 24 years and 10 months (mean duration: 13 years and 7 months) postoperatively as of Dec. 1987. Therefore, patients with well and moderately differentiated adenocarcinomas confined to the bladder and the urachal remnant could be expected to survive longer by en bloc resection.

摘要

1960年至1982年间,8例脐尿管癌患者接受了膀胱部分切除术或整块切除术,其五年生存率为50%。1例高分化腺癌、1例中分化腺癌、1例低分化腺癌和1例移行细胞癌患者在术后6个月至2年2个月死于癌症(平均病程:1年3个月)。高分化腺癌患者接受了整块切除术,术中发现肿瘤有腹膜侵犯。其余3例患者被诊断为肿瘤局限于膀胱和脐尿管残余,接受了膀胱部分切除术。2例肿瘤局限于膀胱和脐尿管残余的高分化和中分化癌患者接受了整块切除术,截至1987年12月,术后存活时间为8年5个月至24年10个月(平均病程:13年7个月)。因此,肿瘤局限于膀胱和脐尿管残余的高分化和中分化腺癌患者通过整块切除术有望获得更长的生存期。

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