作为肌苷-5'-单磷酸脱氢酶（IMPDH）抑制剂的低分子量吲哚片段
Low molecular weight indole fragments as IMPDH inhibitors.
作者信息
Beevers Rebekah E, Buckley George M, Davies Natasha, Fraser Joanne L, Galvin Francis C, Hannah Duncan R, Haughan Alan F, Jenkins Kerry, Mack Stephen R, Pitt William R, Ratcliffe Andrew J, Richard Marianna D, Sabin Verity, Sharpe Andrew, Williams Sophie C
机构信息
UCB Celltech, Granta Park, Great Abington, Cambridge CB1 6GS, UK.
出版信息
Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. doi: 10.1016/j.bmcl.2006.01.089. Epub 2006 Feb 17.
PMID:16483769
Abstract
The study of non-oxazole containing indole fragments as inhibitors of inosine monophosphate dehydrogenase (IMPDH) is described. The synthesis and in vitro inhibitory values for IMPDH II are discussed.
摘要
描述了对作为肌苷单磷酸脱氢酶（IMPDH）抑制剂的不含恶唑的吲哚片段的研究。讨论了IMPDH II的合成及体外抑制值。
Zotero 插件