白蒿（菊科）的杀真菌活性。

Fungicidal activity of Artemisia herba alba Asso (Asteraceae).

作者信息

Saleh Mahmoud A, Belal Mohamed H, el-Baroty Gamal

机构信息

Department of Chemistry, Texas Southern University, Houston, Texas 77004, USA.

出版信息

J Environ Sci Health B. 2006;41(3):237-44. doi: 10.1080/03601230500354774.

DOI:10.1080/03601230500354774

PMID:16484084

Abstract

The antifungal activity of Artemisia herba alba was found to be associated with two major volatile compounds isolated from the fresh leaves of the plant. Carvone and piperitone were isolated and identified by GC/MS, GC/IR, and NMR spectroscopy. Antifungal activity was measured against Penicillium citrinum (ATCC 10499) and Mucora rouxii (ATCC 24905). The antifungal activity (IC50) of the purified compounds was estimated to be 5 microg/ml, 2 microg/ml against Penicillium citrinum and 7 microg/ml, 1.5 microg/ml against Mucora rouxii carvone and piperitone, respectively.

摘要

发现白蒿的抗真菌活性与从该植物新鲜叶片中分离出的两种主要挥发性化合物有关。通过气相色谱/质谱联用仪（GC/MS）、气相色谱/红外光谱联用仪（GC/IR）和核磁共振光谱法（NMR）分离并鉴定了香芹酮和哌啶酮。针对桔青霉（ATCC 10499）和鲁氏毛霉（ATCC 24905）测定了抗真菌活性。纯化化合物的抗真菌活性（IC50）估计分别为：针对桔青霉，香芹酮和哌啶酮的IC50为5微克/毫升、2微克/毫升；针对鲁氏毛霉，香芹酮和哌啶酮的IC50为7微克/毫升、1.5微克/毫升。