从犹太蒿精油中分离出的两种主要成分的生物活性

Bioactivity of two major constituents isolated from the essential oil of Artemisia judaica L.

作者信息

Abdelgaleil Samir A M, Abbassy Moustafa A, Belal Abdel-Salam H, Abdel Rasoul Mona A A

机构信息

Department of Pesticide Chemistry, Faculty of Agriculture, 21545-El-Shatby, Alexandria University, Alexandria, Egypt.

出版信息

Bioresour Technol. 2008 Sep;99(13):5947-50. doi: 10.1016/j.biortech.2007.10.043. Epub 2007 Dec 3.

DOI:10.1016/j.biortech.2007.10.043

PMID:18054484

Abstract

The essential oil of Artemisia judaica L., grown on Sinai Peninsula of Egypt, was extracted via hydrodistillation. Chromatographic separation on repeated silica gel columns led to isolate two compounds namely piperitone and trans-ethyl cinnamate. Insecticidal, antifeedant and antifungal properties of the isolated compounds were examined. Both compounds showed pronounced insecticidal and antifeedant activity against the third instar larvae of Spodoptera littoralis (Boisd). trans-Ethyl cinnamate (LD(50)=0.37 microg/larva) was more toxic than piperitone (LD(50)=0.68microg/larva). The two isolated compounds revealed antifeedant activity in a concentration dependent manner, with complete feeding inhibition at a concentration of 1,000microg/ml. When tested for antifungal activity against four plant pathogenic fungi, the isolated compounds exhibited a moderate to high activity.

摘要

生长在埃及西奈半岛的犹太蒿的精油通过水蒸馏法提取。在反复的硅胶柱上进行色谱分离，分离出两种化合物，即哌啶酮和反式肉桂酸乙酯。对分离出的化合物的杀虫、拒食和抗真菌特性进行了研究。两种化合物对海滨夜蛾（Boisd）的三龄幼虫均表现出显著的杀虫和拒食活性。反式肉桂酸乙酯（LD(50)=0.37微克/幼虫）比哌啶酮（LD(50)=0.68微克/幼虫）毒性更强。两种分离出的化合物以浓度依赖的方式表现出拒食活性，在浓度为1000微克/毫升时完全抑制取食。当对四种植物病原真菌进行抗真菌活性测试时，分离出的化合物表现出中度至高活性。