Chan Jane W
Department of Neurology, University of Nevada School of Medicine, Las Vegas, Nevada 89102, USA.
J Clin Rheumatol. 2006 Feb;12(1):30-1. doi: 10.1097/01.rhu.0000200423.12270.18.
This report describes a 69-year-old woman who presented with acute monocular visual loss, ipsilateral headache, and elevated sedimentation rate and C-reactive protein. Both temporal artery biopsies were negative. Neuroimaging, dural biopsy, and breast biopsy all confirmed the diagnosis of carcinomatous hypertrophic pachymeningitis associated with metastatic breast carcinoma. After treatment with corticosteroids, her vision improved. Her clinical presentation initially mimicked the symptoms and signs of giant cell arteritis. Acute monocular visual loss without other cranial nerve palsies may be an uncommon presentation of hypertrophic pachymeningitis from metastatic breast carcinoma.
本报告描述了一位69岁女性，她出现急性单眼视力丧失、同侧头痛，血沉和C反应蛋白升高。双侧颞动脉活检均为阴性。神经影像学检查、硬脑膜活检和乳腺活检均确诊为与转移性乳腺癌相关的癌性肥厚性硬脑膜炎。使用皮质类固醇治疗后，她的视力有所改善。她最初的临床表现类似于巨细胞动脉炎的症状和体征。无其他颅神经麻痹的急性单眼视力丧失可能是转移性乳腺癌所致肥厚性硬脑膜炎的一种罕见表现。
