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Methysergide in the treatment of narcolepsy.

作者信息

Wyler A R, Wilkus R J, Troupin A S

出版信息

Arch Neurol. 1975 Apr;32(4):265-8. doi: 10.1001/archneur.1975.00490460081012.

DOI:10.1001/archneur.1975.00490460081012
PMID:164849
Abstract

Five patients with narcolepsy (four with the allied symptom of cataplexy) were treated with the serotonin antagonist methysergide. All patients had as good control of their sleep attacks while on methysergide therapy as on a control period of dextroamphetamine therapy. The cataplexy was less well controlled by methysergide than by dextroamphetamine, but improved when compared to a period without medication. Two patients developed severe calf claudication while on methysergide.

摘要

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