Pérez-Calatayud J, Granero D, Ballester F, Crispín V, Van der Laarse R
Physics Section, Radiation Oncology Department, La Fe University Hospital, Avda Campanar 21, E46009 Valencia, Spain.
Med Phys. 2006 Jan;33(1):16-20. doi: 10.1118/1.2138008.
The H-type Leipzig applicators are accessories of the microSelectron-HDR system (Nucletron, Veenendaal, The Netherlands) for treatment of superficial malignancies. Recently, the dose rate distributions in liquid water for the whole set of applicators using both source models available for the microSelectron-HDR afterloaders have been obtained by means of the experimentally validated Monte Carlo (MC) code GEANT4. Also an output table (cGy/hU) at 3 mm depth on the applicator central axis was provided. The output verification of these applicators by the user, prior to their clinical use, present practical problems: small detectors such as thermoluminescent dosimeters or parallel-plate ionization chambers are not easily used for verification in a clinical environment as they require a rigid setup with the Leipzig applicator and a phantom. In contrast, well-type ionization chambers are readily available in radiotherapy departments. This study presents a technique based on the HDR1000Plus well chamber (Standar Imaging) measurements with a special insert, which allows the output verification of the H-type Leipzig applicators on a routine basis. This technique defines correspondence factors (CF) between the in water dose rate output of the Leipzig applicators (cGy/hU) obtained with MC and the reading on the well chamber with the special insert, normalized to the HDR calibration factor with the HDR insert and to the source strength. To commission the applicators (with the well chamber and the special insert used), the physicist should check if the CF value agrees with its tabulated values presented in this work. If the differences are within 5% the tabulated output values can be used in clinical dosimetry. This technique allows the output validation of the Leipzig applicators with a well chamber widely used for HDR Ir-192 source strength measurements. It can easily be adapted to other types of well chambers for HDR source output verification.
H型莱比锡施源器是微Selectron-HDR系统(荷兰维嫩代尔的核通公司)的附件,用于治疗浅表恶性肿瘤。最近,借助经过实验验证的蒙特卡罗(MC)代码GEANT4,已获得了使用微Selectron-HDR后装治疗机可用的两种源模型的整套施源器在液态水中的剂量率分布。还提供了施源器中心轴上3毫米深度处的输出表(cGy/hU)。用户在临床使用这些施源器之前进行输出验证存在实际问题:诸如热释光剂量计或平行板电离室等小型探测器在临床环境中不易用于验证,因为它们需要与莱比锡施源器和模体进行刚性设置。相比之下,井型电离室在放射治疗科室很容易获得。本研究提出了一种基于使用特殊插入物的HDR1000Plus井型电离室测量的技术,该技术允许对H型莱比锡施源器进行常规输出验证。该技术定义了用MC获得的莱比锡施源器在水中的剂量率输出(cGy/hU)与带有特殊插入物的井型电离室读数之间的对应因子(CF),并根据使用HDR插入物的HDR校准因子和源强进行归一化。为了调试施源器(使用井型电离室和特殊插入物),物理学家应检查CF值是否与其在本工作中列出的值一致。如果差异在5%以内,则列出的输出值可用于临床剂量测定。该技术允许使用广泛用于HDR铱-192源强测量的井型电离室对莱比锡施源器进行输出验证。它可以很容易地适用于其他类型的用于HDR源输出验证的井型电离室。