镱-169高剂量率近距离治疗源的蒙特卡罗特性及统计不确定性分析

Monte Carlo characterization of an ytterbium-169 high dose rate brachytherapy source with analysis of statistical uncertainty.

作者信息

Medich David C, Tries Mark A, Munro John J

机构信息

Radiation Laboratory, University of Massachusetts Lowell, 1 University Avenue, Lowell, Massachusetts 01854, USA.

出版信息

Med Phys. 2006 Jan;33(1):163-72. doi: 10.1118/1.2147767.

DOI:10.1118/1.2147767

PMID:16485423

Abstract

An ytterbium-169 high dose rate brachytherapy source, distinguished by an intensity-weighted average photon energy of 92.7 keV and a 32.015 +/- 0.009 day half-life, is characterized in terms of the updated AAPM Task Group Report No. 43 specifications using the MCNP5 Monte Carlo computer code. In accordance with these specifications, the investigation included Monte Carlo simulations both in water and air with the in-air photon spectrum filtered to remove low-energy photons below 10 keV. TG-43 dosimetric data including S(K), D(r, lamda), lambda, gL(r), F(r, lamda), phi an(r), and phi(an) were calculated and statistical uncertainties in these parameters were derived and calculated in the appendix.

摘要

一种镱-169高剂量率近距离放射治疗源，其特征在于强度加权平均光子能量为92.7 keV，半衰期为32.015±0.009天，根据更新后的美国医学物理师协会任务组报告第43号规范，使用MCNP5蒙特卡罗计算机代码进行了表征。按照这些规范，该研究包括在水和空气中的蒙特卡罗模拟，其中空气中的光子能谱经过滤波以去除能量低于10 keV的低能光子。计算了包括S(K)、D(r,λ)、λ、gL(r)、F(r,λ)、φan(r)和φ(an)在内的TG-43剂量学数据，并在附录中推导并计算了这些参数的统计不确定性。