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用于高能近距离放射治疗剂量测定的甲酸锂电子顺磁共振剂量计的射束质量和模体散射校正的蒙特卡罗计算

Monte Carlo Calculation of Beam Quality and Phantom Scatter Corrections for Lithium Formate Electron Paramagnetic Resonance Dosimeter for High-energy Brachytherapy Dosimetry.

作者信息

Mishra Subhalaxmi, Selvam T Palani

机构信息

Bhabha Atomic Research Centre, Radiological Physics and Advisory Division, Health, Safety and Environment Group, Mumbai, Maharashtra, India.

出版信息

J Med Phys. 2017 Apr-Jun;42(2):72-79. doi: 10.4103/jmp.JMP_95_16.

Abstract

PURPOSE

To investigate beam quality correction, () and phantom scatter correction, () for lithium formate dosimeter as a function of distance r along the transverse axis of the high-energy brachytherapy sources Co, Cs, Ir and Yb using the Monte Carlo-based EGSnrc code system.

MATERIALS AND METHODS

The brachytherapy sources investigated in this study are BEBIG High Dose Rate (HDR) Co (model Co0.A86), Cs (model RTR), HDR Ir (model Microselectron) and HDR Yb (model 4140). The solid phantom materials investigated are PMMA, polystyrene, solid water, virtual water, plastic water, RW1, RW3, A150 and WE210.

RESULT

() is about unity and distance independent fo Co, Cs and Ir brachytherapy sources, whereas for the Yb source, () increases gradually to about 4 % larger than unity at a distance of 15 cm along the transverse axis of the source. For Co source, phantoms such as polystyrene, plastic water, solid water, virtual water, RW1, RW3 and WE210 are water-equivalent but PMMA and A150 phantoms show distance-dependent () values. For Cs and Ir sources, phantoms such as solid water, virtual water, RW1, RW3 and WE210 are water-equivalent. However, phantoms such as PMMA, plastic water, polystyrene and A150 showed distance-dependent () values, for these sources. For Yb source, all the investigated phantoms show distance-dependent () values.

CONCLUSION

() is about unity and distance independent for Co, Cs and Ir brachytherapy sources. Phantoms such as solid water, virtual water, RW1, RW3 and WE210 are water-equivalent for Co, Cs and Ir brachytherapy sources. For Yb source, all the investigated phantoms show distance-dependent () values.

摘要

目的

使用基于蒙特卡罗方法的EGSnrc代码系统,研究甲酸锂剂量计的射束质量校正()和体模散射校正()随沿高能近距离放射治疗源钴、铯、铱和镱横向轴距离r的变化情况。

材料与方法

本研究中所研究的近距离放射治疗源为BEBIG高剂量率(HDR)钴源(型号Co0.A86)、铯源(型号RTR)、HDR铱源(型号Microselectron)和HDR镱源(型号4140)。所研究的固体体模材料有聚甲基丙烯酸甲酯(PMMA)、聚苯乙烯、固体水、虚拟水、塑料水、RW1、RW3、A150和WE210。

结果

对于钴、铯和铱近距离放射治疗源,()约为1且与距离无关,而对于镱源,在沿源横向轴15 cm处,()逐渐增大至比1大4%左右。对于钴源,聚苯乙烯、塑料水、固体水、虚拟水、RW1、RW3和WE210等体模与水等效,但PMMA和A150体模显示出与距离相关 的()值。对于铯和铱源,固体水、虚拟水、RW1、RW3和WE210等体模与水等效。然而,对于这些源,PMMA、塑料水、聚苯乙烯和A150等体模显示出与距离相关的()值。对于镱源,所有研究的体模均显示出与距离相关的()值。

结论

对于钴、铯和铱近距离放射治疗源,()约为1且与距离无关。对于钴、铯和铱近距离放射治疗源,固体水、虚拟水、RW1、RW3和WE210等体模与水等效。对于镱源,所有研究的体模均显示出与距离相关的()值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a012/5496273/831731edb832/JMP-42-72-g002.jpg

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