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使用131I-碘油消融复发性原发性肝癌

Ablation of recurrent primary liver cancer using 131I-lipiodol.

作者信息

Novell R, Hilson A, Hobbs K

机构信息

Academic Department of Surgery, Royal Free Hospital School of Medicine, London, UK.

出版信息

Postgrad Med J. 1991 Apr;67(786):393-5. doi: 10.1136/pgmj.67.786.393.

DOI:10.1136/pgmj.67.786.393
PMID:1648718
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2398799/
Abstract

A case of recurrent hepatocellular carcinoma following resection is reported. The patient received 2 treatments of 131I-lipiodol administered via the hepatic artery at angiography. Good localization in tumour tissue was observed on subsequent computed tomographic scans and no adverse effects were seen after either treatment. After the first treatment 2 nodules of recurrent tumour were resected and proved to be totally necrotic. The patient remains well 9 months later with a persistently elevated serum alphafetoprotein but no evidence of residual tumour. It is suggested that 131I-lipiodol may be the treatment of choice for small tumours in elderly high-risk patients.

摘要

本文报告了1例肝癌切除术后复发的病例。该患者在血管造影时经肝动脉接受了2次131I-碘油治疗。在随后的计算机断层扫描中观察到肿瘤组织有良好的定位,且每次治疗后均未出现不良反应。第一次治疗后,切除了2个复发性肿瘤结节,病理证实完全坏死。9个月后患者情况良好,血清甲胎蛋白持续升高,但无残留肿瘤迹象。提示131I-碘油可能是老年高危患者小肿瘤的首选治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddec/2398799/6e7e7c6e5a51/postmedj00076-0075-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddec/2398799/79061556e954/postmedj00076-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddec/2398799/b807cfcc4b8a/postmedj00076-0075-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddec/2398799/6e7e7c6e5a51/postmedj00076-0075-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddec/2398799/79061556e954/postmedj00076-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddec/2398799/b807cfcc4b8a/postmedj00076-0075-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddec/2398799/6e7e7c6e5a51/postmedj00076-0075-c.jpg

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引用本文的文献

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In vitro assessment of Lipiodol-targeted radiotherapy for liver and colorectal cancer cell lines.碘油靶向放射治疗对肝癌和结肠癌细胞系的体外评估。
Br J Cancer. 1999 Apr;79(11-12):1665-71. doi: 10.1038/sj.bjc.6690266.

本文引用的文献

1
Primary hepatocellular carcinoma--etiology, pathogenesis, and prevention.原发性肝细胞癌——病因、发病机制及预防
Hum Pathol. 1981 Dec;12(12):1085-97. doi: 10.1016/s0046-8177(81)80329-2.
2
Hepatocellular carcinoma: treatment with intraarterial iodized oil with and without chemotherapeutic agents.肝细胞癌:使用和不使用化疗药物的动脉内碘化油治疗。
Radiology. 1987 May;163(2):345-51. doi: 10.1148/radiology.163.2.3031724.
3
Hepatocellular carcinoma detected by iodized oil. Use of anticancer agents.
Radiology. 1985 Jan;154(1):25-9. doi: 10.1148/radiology.154.1.2981114.
4
Morbidity and mortality after major hepatic resection in cirrhotic patients with hepatocellular carcinoma.肝细胞癌肝硬化患者行肝大部切除术后的发病率和死亡率
HPB Surg. 1988 Sep;1(1):45-56; discussion 56. doi: 10.1155/1988/93437.
5
Hepatic artery injection of I-131-labeled lipiodol. Part II. Preliminary results of therapeutic use in patients with hepatocellular carcinoma and liver metastases.肝动脉注射碘-131标记的碘油。第二部分。肝细胞癌和肝转移瘤患者治疗应用的初步结果。
Radiology. 1988 Aug;168(2):547-50. doi: 10.1148/radiology.168.2.2839867.
6
Hepatic artery injection of I-131-labeled lipiodol. Part I. Biodistribution study results in patients with hepatocellular carcinoma and liver metastases.肝动脉注射碘-131标记的碘油。第一部分。肝细胞癌和肝转移患者的生物分布研究结果。
Radiology. 1988 Aug;168(2):541-5. doi: 10.1148/radiology.168.2.2839866.
7
Biodistribution and in vivo kinetics of iodine-131 lipiodol infused via the hepatic artery of patients with hepatic cancer.经肝动脉注入碘-131 碘化油在肝癌患者体内的生物分布及体内动力学
J Nucl Med. 1988 Jun;29(6):1066-77.
8
Dosimetry of iodine-131 ethiodol in the treatment of hepatoma.
J Nucl Med. 1988 Jun;29(6):1038-44.
9
Resectability rate of hepatocellular carcinoma in rural southern Africans.非洲南部农村地区肝细胞癌的可切除率
Br J Surg. 1988 Apr;75(4):335-8. doi: 10.1002/bjs.1800750413.
10
Metastatic nodules of hepatocellular carcinoma: detection with angiography, CT, and US.
Radiology. 1987 Oct;165(1):61-3. doi: 10.1148/radiology.165.1.2819941.