Huber F-X, Hillmeier J, Herzog L, McArthur N, Kock H-J, Meeder P J
Surgical Clinic, Division of Traumatology and Reconstructive Surgery, University of Heidelberg, Heidelberg, Germany.
J Hand Surg Br. 2006 Jun;31(3):298-303. doi: 10.1016/j.jhsb.2005.12.006. Epub 2006 Feb 17.
In a prospective study, we used the nanocrystalline hydroxyapatite paste Ostim (Osartis, Obernburg, Germany) in combination with a palmar plate to treat comminuted radius fractures with a metaphyseal and articular component in order to examine the clinical use of Ostim as a bone substitute. Twenty-one patients with 22 radius fractures of AO types C2 and C3 were included in the study. The measurements, taken 10.2+/-1.3 months after the initial treatment, revealed a dorsopalmar tilt of 8.8+/-3.7 degrees , a radioulnar inclination of 18.8+/-2.8 degrees and an ulnar variance of 0.8+/-1.8mm. According to the Gartland and Werley evaluation, eight of the treated fractures attained an excellent, 11 a good and the remaining three a fair result. The study demonstrates that Ostim, in combination with angularly stable osteosynthesis, can be used as an acceptable bone substitute for the treatment of type C2 and C3 radial fractures.
在一项前瞻性研究中,我们使用纳米晶羟基磷灰石糊剂Ostim(Osartis,德国奥伯恩堡)联合掌板治疗伴有干骺端和关节成分的粉碎性桡骨骨折,以研究Ostim作为骨替代物的临床应用。该研究纳入了21例患者的22处AO C2型和C3型桡骨骨折。在初始治疗后10.2±1.3个月进行测量,结果显示掌背侧倾斜度为8.8±3.7度,桡尺倾斜度为18.8±2.8度,尺骨差异为0.8±1.8mm。根据Gartland和Werley评估,所治疗的骨折中有8例结果为优,11例为良,其余3例为尚可。该研究表明,Ostim联合角度稳定的骨固定术可作为治疗C2型和C3型桡骨骨折的一种可接受的骨替代物。