前房穿刺细胞学检查（细胞离心涂片技术）用于诊断眼内淋巴瘤。
Anterior chamber paracentesis cytology (cytospin technique) for the diagnosis of intraocular lymphoma.
作者信息
Finger P T, Papp C, Latkany P, Kurli M, Iacob C E
机构信息
The New York Eye Cancer Center, 115 E 61st Street, New York City, NY 10021, USA.
出版信息
Br J Ophthalmol. 2006 Jun;90(6):690-2. doi: 10.1136/bjo.2005.087346. Epub 2006 Feb 17.
AIM
To report on the diagnosis of intraocular lymphoma by aqueous cytology.
METHODS
Four patients suspected of having intraocular lymphoma were evaluated by anterior chamber (AC) paracentesis with cytology (cytospin technique). All had a history of non-ocular lymphoma and presented with at least one plus anterior chamber cells despite intensive glucocorticoid therapy. A 25 gauge needle was inserted through clear cornea (bevel up), over the iris stroma, so as to drain the AC. The aqueous humour was sent for cytopathology (cytospin technique), culture, and sensitivity tests.
RESULTS
All procedures were diagnostic. Three were lymphoma and the fourth was culture positive for Propionibacterium endophthalmitis. No secondary glaucoma, hyphaema, cataract or infections were related to AC paracentesis.
CONCLUSIONS
In this series, AC aspiration cytology enhanced by the cytospin technique was an effective, minimally invasive alternative to vitrectomy based biopsy. This technique should be considered to rule in the diagnosis of intraocular lymphoma in selected cases with cells in the anterior chamber.
目的
报告通过房水细胞学诊断眼内淋巴瘤。
方法
对4例疑似眼内淋巴瘤患者进行前房穿刺并进行细胞学检查（细胞离心涂片技术）。所有患者均有非眼内淋巴瘤病史，尽管接受了强化糖皮质激素治疗，但前房细胞至少为1+。用25号针头经透明角膜（斜面向上）插入虹膜基质上方，以引流前房。将房水送去进行细胞病理学检查（细胞离心涂片技术）、培养和药敏试验。
结果
所有操作均具有诊断价值。3例为淋巴瘤，第4例培养结果显示为丙酸杆菌性眼内炎阳性。未发现继发性青光眼、前房积血、白内障或感染与前房穿刺有关。
结论
在本系列研究中，通过细胞离心涂片技术强化的前房穿刺细胞学检查是一种有效的、微创的替代玻璃体切割活检的方法。对于前房有细胞的特定病例，应考虑采用该技术来确诊眼内淋巴瘤。
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