Kirmani M H, Thomas E L, Rao N A, Laborde R P
Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles 90033.
Br J Ophthalmol. 1987 Oct;71(10):748-52. doi: 10.1136/bjo.71.10.748.
A patient with uveitis and retinal pigment epithelial detachments underwent an extensive medical examination and pars plana vitrectomy in an attempt to confirm the clinical diagnosis of reticulum cell sarcoma. None of these examinations revealed the presence of malignancy. Transscleral biopsy of subretinal lesions confirmed the histopathological diagnosis of reticulum cell sarcoma. The patient was begun on systemic chemotherapy and external beam radiation to the eye and orbit, with resultant preservation of the eye, vision, and probable extension of life because of early detection of reticulum cell sarcoma by choroidal biopsy. This technique may be advantageous in the diagnosis cases of eyes with clinical evidence of reticulum cell sarcoma, no systemic signs of malignancy, and negative vitreous biopsies.
一名患有葡萄膜炎和视网膜色素上皮脱离的患者接受了全面的医学检查和平部玻璃体切除术，以试图确诊网状细胞肉瘤的临床诊断。这些检查均未发现恶性肿瘤的存在。视网膜下病变的经巩膜活检证实了网状细胞肉瘤的组织病理学诊断。该患者开始接受全身化疗以及眼部和眼眶的外照射放疗，由于通过脉络膜活检早期发现了网状细胞肉瘤，从而保住了眼睛、视力，并可能延长了生命。这项技术在诊断那些有网状细胞肉瘤临床证据、无全身恶性体征且玻璃体活检为阴性的眼部病例中可能具有优势。
