Nielsen G P, Isaksson H J, Finnbogason H, Gunnlaugsson G H
Department of Pathology, University of Iceland, Reykjavik.
APMIS. 1991 Jul;99(7):653-6. doi: 10.1111/j.1699-0463.1991.tb01241.x.
We report seven cases of adenocarcinoma of the vermiform appendix occurring in Iceland during 1974-1989. The patients ranged in age from 25-83 years, mean age 55.1 years. There were five males and two females. Five had mucinous adenocarcinoma, two had adenocarcinoma. Four patients presented with symptoms and signs of acute appendicitis and all had surgically resectable disease. Three of these patients were alive with no evidence of disease four months, two years and 15 years after presentation; one death of disease occurred seven years after ileocecal resection. In three cases, the clinical presentation was that of metastatic adenocarcinoma of unknown origin. Of these patients two were diagnosed at autopsy and one after appendectomy for perforated appendicitis. Survival in this group was six weeks, three months and twelve months, respectively. In none of our patients was the diagnosis made preoperatively and no tumors were found in appendices removed incidental to other intra-abdominal operations. The incidence of adenocarcinoma of the vermiform appendix in Iceland during 1974-1989 was approximately 0.2 cases/100.000/year.
我们报告了1974年至1989年期间在冰岛发生的7例阑尾腺癌病例。患者年龄在25岁至83岁之间，平均年龄55.1岁。其中男性5例，女性2例。5例为黏液腺癌，2例为腺癌。4例患者表现为急性阑尾炎的症状和体征，所有患者的疾病均可通过手术切除。这些患者中有3例在就诊后4个月、2年和15年时存活且无疾病证据；1例患者在回盲部切除术后7年死于疾病。3例患者的临床表现为不明来源的转移性腺癌。其中2例患者在尸检时被诊断，1例在阑尾穿孔切除术后被诊断。该组患者的生存期分别为6周、3个月和12个月。我们所有患者均未在术前确诊，且在其他腹部手术中 incidental 切除的阑尾中未发现肿瘤。1974年至1989年期间冰岛阑尾腺癌的发病率约为0.2例/10万/年。 （注：原文中“incidental”有误，可能是“incidentally”，这里按原文翻译）
