与激素替代疗法和含铁血黄素沉着症相关的肝腺瘤病：一例报告
Hepatic adenomatosis associated with hormone replacement therapy and hemosiderosis: a case report.
作者信息
Hagiwara Satoshi, Takagi Hitoshi, Kanda Daisuke, Sohara Naondo, Kakizaki Satoru, Katakai Kenji, Yoshinaga Teruo, Higuchi Tsugio, Nomoto Kenichi, Kuwano Hiroyuki, Mori Masatomo
机构信息
Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa, Maebashi, Gunma 371-8511, Japan.
出版信息
World J Gastroenterol. 2006 Jan 28;12(4):652-5. doi: 10.3748/wjg.v12.i4.652.
We have reported a case of hepatic adenomatosis associated with hormone replacement therapy (estrogen and progesterone) and hemosiderosis caused by excessive blood transfusion for the treatment of chronic myeloid leukemia. A 34-year-old woman was found to have several hepatic tumors on a routine medical examination. The general condition was good. Laboratory studies showed iron overload. Abdominal computed tomography and selective hepatic angiography showed several hypervascular tumors in the right lobe of the liver (up to 20 mm in diameter). Since hepatocellular carcinoma could not be ruled out, subsegmental hepatectomy was performed. Histopathological examination of the surgical specimen showed hepatic adenomatosis with hemosiderosis. Both hormone replacement therapy and iron overload could be the cause of hepatic adenomatosis.
我们报告了一例与激素替代疗法（雌激素和孕激素）相关的肝腺瘤病，以及因慢性髓性白血病过度输血导致的含铁血黄素沉着症。一名34岁女性在常规体检中被发现有多个肝脏肿瘤。一般情况良好。实验室检查显示铁过载。腹部计算机断层扫描和选择性肝血管造影显示肝脏右叶有多个高血运肿瘤（直径达20毫米）。由于不能排除肝细胞癌，遂进行了亚肝段切除术。手术标本的组织病理学检查显示为伴有含铁血黄素沉着症的肝腺瘤病。激素替代疗法和铁过载都可能是肝腺瘤病的病因。
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