Millership S, Harris J, Batchelor N
Essex Health Protection Unit, Witham and Department of Microbiology, Princess Alexandra Hospital, Harlow, Essex, UK.
Epidemiol Infect. 2006 Apr;134(2):301-5. doi: 10.1017/S0950268805005091.
The study was undertaken in response to local concerns of a rising number of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections. All patients resident in the community in Essex at the time of diagnosis with a first isolate of MRSA between 1994 and 2001 identified by the diagnostic microbiology laboratory were included. Although the annual incidence rose throughout the study period the majority of those with MRSA (82%) had had hospital contact within the last 5 years. The subset of patients without hospital contact had a median age of 79.5 years, 63% were female and 32% were residents of care homes. Carriage in this population was detected for up to 41 months post-diagnosis. Neither antibiogram nor clinical presentation distinguished these isolates from local hospital-acquired strains.
该研究是针对当地社区获得性耐甲氧西林金黄色葡萄球菌(MRSA)感染病例数不断增加的情况而开展的。纳入了1994年至2001年间由诊断微生物实验室确诊为首次分离出MRSA的埃塞克斯郡社区所有居民患者。尽管在整个研究期间年发病率有所上升,但大多数MRSA患者(82%)在过去5年内曾与医院有过接触。没有医院接触史的患者亚组中位年龄为79.5岁,63%为女性,32%为养老院居民。在该人群中,诊断后长达41个月都检测到了病菌携带情况。无论是抗菌谱还是临床表现都无法将这些分离株与当地医院获得的菌株区分开来。