Mo Jun, Lampkin Beatrice, Perentesis John, Poole Linda, Bao Liming
Division of Pathology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, OH, USA.
Cancer Genet Cytogenet. 2006 Feb;165(1):75-8. doi: 10.1016/j.cancergencyto.2005.10.017.
A complex three-way t(8;18;16)(p11;q21;p13) was detected in a 15-month-old patient with acute myeloid leukemia (AML). The patient had typical clinical manifestation and bone marrow features of AML subtype M5b associated with t(8;16)(p11;p13). Therefore, we believe that the t(8;18;16) is a new variant of t(8;16) related to AML M4/M5. We also review other t(8;16)(p11;p13) variants reported in the literature.