Lagu Tara, Anderson Bradley J, Stein Michael
Department of Medicine and Community Health, Brown Medical School, Providence, RI 02912, USA.
J Subst Abuse Treat. 2006 Mar;30(2):129-33. doi: 10.1016/j.jsat.2005.05.010.
The distribution of naloxone to heroin users is a suggested intervention to reduce overdose and death rates. However, the level of willingness of drug users to administer this medication to others is unclear. Drug users recruited from the community between January 2002 and January 2004 completed a structured interview that assessed topics including drug use, overdose history, and attitudes toward using overdose remedies to assist others. Of the 329 drug users, 82% had used heroin and 64.3% reported that they had injected drugs. Nearly two thirds (64.6%) said that they had witnessed a drug overdose and more than one third (34.6%) had experienced an accidental drug overdose. Most participants (88.5%) said that they would be willing to administer a medication to another drug user in the event of an overdose. Participants who had used heroin (p = .024), had injected drugs (p = .022), had witnessed a drug overdose (p = .001), or had a history of one or more accidental drug overdoses (p = .009) were significantly more willing to treat a companion who had overdosed. Drug users were willing to use naloxone in the event of a friend's overdose. Specific drug use and overdose histories were associated with the greatest willingness to administer naloxone.
向海洛因使用者分发纳洛酮是一项旨在降低过量用药及死亡率的建议干预措施。然而，吸毒者向他人施用这种药物的意愿程度尚不清楚。2002年1月至2004年1月期间从社区招募的吸毒者完成了一项结构化访谈，该访谈评估了包括吸毒情况、过量用药史以及对使用过量用药补救措施帮助他人的态度等主题。在329名吸毒者中，82%使用过海洛因，64.3%报告称他们曾注射过毒品。近三分之二（64.6%）的人表示他们曾目睹过药物过量，超过三分之一（34.6%）的人曾经历过意外药物过量。大多数参与者（88.5%）表示，在发生药物过量时，他们愿意给另一名吸毒者施用药物。使用过海洛因的参与者（p = 0.024）、注射过毒品的参与者（p = 0.022）、目睹过药物过量的参与者（p = 0.001）或有一次或多次意外药物过量史的参与者（p = 0.009）明显更愿意救治过量用药的同伴。吸毒者愿意在朋友过量用药时使用纳洛酮。特定的吸毒情况和过量用药史与施用纳洛酮的最大意愿相关。
