聚维酮碘产品对牙周病原菌的疗效。
The efficacy of povidone-iodine products against periodontopathic bacteria.
作者信息
Nakagawa Taneaki, Hosaka Yasuo, Ishihara Kazuyuki, Hiraishi Toru, Sato Soh, Ogawa Tomohisa, Kamoi Kyuichi
机构信息
Department of Dentistry and Oral Surgery, Medical School Keio University, Keio, Japan.
出版信息
Dermatology. 2006;212 Suppl 1:109-11. doi: 10.1159/000089208.
A total of 8 strains of 6 bacterial species, Porphyromonas gingivalis ATCC33277 and TDC286, Actinobacillus actinomycetemcomitans ATCC29523 and JP2, Fusobacterium nucleatum No. 2, Tannerella forsythensis ATCC43937, Prevotella intermedia ATCC25611 and Streptococcus anginosus ATCC33397, were treated with povidone-iodine (PVP-I) gargle (PVP-I: 0.47 and 0.23% w/v) or chlorhexidine gluconate (CHG) gargle (CHG: 0.002% w/v) for 15, 30 or 60 s, after which they were inoculated into various media, cultured and counted for residual bacteria. At both concentrations, PVP-I gargle reduced the viable cell count of all 8 bacterial strains to below the measurable limit within 15 s. By contrast, there were more than 1,000 viable colonies 60 s following treatment with the CHG gargle. The results demonstrate that povidone-iodine gargle has rapid bactericidal activity against the causative bacteria of periodontal disease.
总共8株6种细菌，即牙龈卟啉单胞菌ATCC33277和TDC286、伴放线放线杆菌ATCC29523和JP2、具核梭杆菌2号、福赛坦氏菌ATCC43937、中间普氏菌ATCC25611和星座链球菌ATCC33397，用聚维酮碘（PVP-I）漱口水（PVP-I：0.47%和0.23% w/v）或葡萄糖酸洗必泰（CHG）漱口水（CHG：0.002% w/v）处理15、30或60秒，之后将它们接种到各种培养基中，进行培养并计数残留细菌。在两种浓度下，PVP-I漱口水在15秒内将所有8株细菌的活菌数降至可测量极限以下。相比之下，用CHG漱口水处理60秒后仍有超过1000个活菌菌落。结果表明，聚维酮碘漱口水对牙周病致病菌具有快速杀菌活性。
Zotero 插件