Gupte G L, Beath S V, Kelly D A, Millar A J W, Booth I W
Liver Unit, Birmingham Children's Hospital, Birmingham, UK.
Arch Dis Child. 2006 Mar;91(3):259-64. doi: 10.1136/adc.2004.068684.
Successful long term parenteral nutrition has transformed the prognosis for children with irreversible intestinal failure in the last three decades, but has also highlighted the long term complications: intestinal failure associated liver disease; recurrent catheter sepsis; and impaired venous access. Recent advances in small bowel transplantation and non-transplant surgical techniques now offer hope of sustained survival in the future without parenteral nutrition.
在过去三十年中,成功的长期肠外营养改变了患有不可逆肠衰竭儿童的预后,但也凸显了长期并发症:肠衰竭相关肝病;反复发生的导管败血症;以及静脉通路受损。小肠移植和非移植手术技术的最新进展为未来无需肠外营养即可实现持续生存带来了希望。