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活动记录仪在失眠症中的验证

Actigraphy validation with insomnia.

作者信息

Lichstein Kenneth L, Stone Kristen C, Donaldson James, Nau Sidney D, Soeffing James P, Murray David, Lester Kristin W, Aguillard R Neal

机构信息

Sleep Research Project, Department of Psychology, The University of Alabama, Tuscaloosa 35487-0348, USA.

出版信息

Sleep. 2006 Feb;29(2):232-9.

PMID:16494091
Abstract

STUDY OBJECTIVE

Actigraphy, a method of inferring sleep from the presence or absence of wrist movement, has been well validated against polysomnography in trials with people without insomnia. However, the small amount of literature on validation with insomniacs has revealed an actigraphy bias toward overscoring sleep. The current validation trial with insomniacs used the largest number of subjects to date in such research and attracted participants with diverse demographic characteristics.

DESIGN

People with insomnia slept 1 night in the laboratory while simultaneously being monitored by polysomnography, actigraphy (high-sensitivity algorithm of the Mini Mitter AW64 Actiwatch), and morning sleep diary.

SETTING

Sleep disorders center.

PARTICIPANTS

Participants were 57 volunteers from the community, 26 men and 31 women, ranging in age from 21 to 87 years. All participants satisfied conservative criteria for insomnia. The sample included subjects with primary insomnia, subjects with comorbid insomnia, and hypnotic users with current insomnia complaints.

INTERVENTIONS

N/A.

MEASUREMENTS AND RESULTS

Actigraphy was successfully validated on 4 measures of sleep pattern--number of awakenings, wake time after sleep onset, total sleep time, and sleep efficiency percentage--based on nonsignificant mean differences and significant correlation between actigraphy and polysomnography. Sleep-onset latency with actigraphy was not significantly different from polysomnography but was weakly correlated with polysomnography. Hypnotic use contributed to actigraphic overscoring of sleep.

CONCLUSIONS

Actigraphy proved to be a satisfactory objective measure of sleep on 4 of 5 sleep parameters, but these results are specific to this particular instrument using this particular algorithm and should not be construed as a blanket endorsement of actigraphy for measuring insomnia.

摘要

研究目的

活动记录仪是一种通过手腕活动与否来推断睡眠情况的方法,在针对无失眠症人群的试验中,已与多导睡眠图进行了充分验证。然而,关于失眠症患者验证的少量文献显示,活动记录仪存在对睡眠时间过度计分的偏差。当前针对失眠症患者的验证试验在这类研究中使用了迄今为止最多的受试者数量,并吸引了具有不同人口统计学特征的参与者。

设计

失眠症患者在实验室睡一晚,同时接受多导睡眠图、活动记录仪(Mini Mitter AW64活动记录仪的高灵敏度算法)和早晨睡眠日记的监测。

地点

睡眠障碍中心。

参与者

参与者为57名来自社区的志愿者,26名男性和31名女性,年龄在21岁至87岁之间。所有参与者均符合保守的失眠症标准。样本包括原发性失眠症患者、共病失眠症患者以及有当前失眠主诉的催眠药物使用者。

干预措施

无。

测量与结果

基于活动记录仪与多导睡眠图之间无显著的平均差异以及显著的相关性,活动记录仪在睡眠模式的4项测量指标上——觉醒次数、睡眠开始后的清醒时间、总睡眠时间和睡眠效率百分比——得到了成功验证。活动记录仪测得的入睡潜伏期与多导睡眠图无显著差异,但与多导睡眠图的相关性较弱。使用催眠药物导致活动记录仪对睡眠时间过度计分。

结论

活动记录仪在5项睡眠参数中的4项上被证明是一种令人满意的睡眠客观测量方法,但这些结果特定于使用该特定算法的这一特定仪器,不应被视为对使用活动记录仪测量失眠症的全面认可。

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