Godtfredsen Nina S, Prescott Eva, Osler Merete
Københavns Kommunehospital, Institut for Sygdomsforebyggelse, Hovedstadens Center for Prospektive Befolkningsstudier, H:S Rigshospitalet, Kardiologisk Afdeling, og Københavns Universitet.
Ugeskr Laeger. 2006 Feb 13;168(7):695-7.
The purpose of this cohort study with up to 31 years of follow-up of 19,714 persons from three Danish population-based studies was to analyse the association between smoking reduction and lung cancer risk. Information on smoking habits and changes in these were linked to the Danish Cancer Registry for incident lung cancers and analysed with Cox regression. Results showed that compared to sustained heavy smokers, smoking reduction by at least 50% reduced lung cancer incidence by 27%. We conclude that smoking reduction is associated with a significantly reduced risk of lung cancer.
这项队列研究对来自丹麦三项基于人群的研究中的19714人进行了长达31年的随访,其目的是分析吸烟量减少与肺癌风险之间的关联。吸烟习惯及其变化的信息与丹麦癌症登记处关于肺癌发病情况的信息相关联,并通过Cox回归进行分析。结果显示,与持续重度吸烟者相比,吸烟量减少至少50%可使肺癌发病率降低27%。我们得出结论,吸烟量减少与肺癌风险显著降低相关。