Kollin Claude, Hesser Ulf, Ritzén E Martin, Karpe Bengt
Department of Woman and Child Health, Karolinska Institut, Stockholm, Sweden.
Acta Paediatr. 2006 Mar;95(3):318-24. doi: 10.1080/08035250500423812.
To study whether surgical treatment at age 9 mo in boys with congenital unilaterally palpable undescended testes (cryptorchidism) is followed by improved growth of the previously retained testes compared to non-treatment.
At the age of 6 mo, 70 boys were randomized to surgical treatment at 9 mo and 79 boys to treatment at 3 y of age. The boys were then followed at 12 and 24 mo. Ultrasonography was used to determine testicular volume.
After orchidopexy, the previously retained testes resumed growth and were significantly larger than the non-operated testes at 2 y (0.49 ml vs 0.36 ml, p<0.001). Testicular growth after orchidopexy was also demonstrated by a higher mean ratio between the previously retained and the scrotal testes of the individual boys at 2 y: 0.84 for the surgically treated group, compared to 0.63 for the untreated group (p<0.001).
Surgery at 9 mo has a beneficial effect on the growth of previously undescended testes.
研究9个月大的先天性单侧可触及隐睾(睾丸未降)男孩接受手术治疗后,与未治疗相比,先前留存睾丸的生长是否得到改善。
6个月大时,70名男孩被随机分为9个月时接受手术治疗组,79名男孩被分为3岁时接受治疗组。然后在12个月和24个月时对这些男孩进行随访。使用超声检查来确定睾丸体积。
睾丸固定术后,先前留存的睾丸恢复生长,在2岁时明显大于未手术的睾丸(0.49毫升对0.36毫升,p<0.001)。睾丸固定术后睾丸生长还表现为,在2岁时,个体男孩先前留存睾丸与阴囊内睾丸的平均比值更高:手术治疗组为0.84,未治疗组为0.63(p<0.001)。
9个月时进行手术对先前未降睾丸的生长有有益影响。