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[精神药理学药物急性中毒所致中毒性缺氧性脑病发生过程中一些实验室参数的发病机制意义]

[Pathogenetic implication of some laboratory parameters in the development of toxicohypoxic encephalopathy in acute poisoning by psychopharmacological agents].

作者信息

Il'iashenko K K, Khvatov V B, Golikov P P, Evgrafov S Iu, Lezhenina N F, El'kov A N

出版信息

Anesteziol Reanimatol. 2005 Nov-Dec(6):12-5.

Abstract

In 62 patients with acute poisoning, blood gases, immunograms, hemorheology, oxidative stress, and the blood levels of biogenic amines were studied at the toxicogenic and somatogenic stages of poisoning. It was found that the development of toxicohypoxic encephalopathy was affected by the magnitude of changes in laboratory homeostatic parameters among which hemorheological and immunological were prominent.

摘要

对62例急性中毒患者在中毒的致毒阶段和躯体阶段研究了血气、免疫图谱、血液流变学、氧化应激以及生物胺的血药浓度。结果发现,实验室稳态参数的变化幅度,尤其是血液流变学和免疫学参数的变化幅度,会影响中毒性缺氧性脑病的发生发展。

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