Sarwar Shahzad, Alam Altaf, Khan Anwaar A
Department of Gastroenterology, Adelaide and Meath Hospital Tallaght Dublin 24, Ireland.
J Coll Physicians Surg Pak. 2006 Feb;16(2):97-100.
To determine the changes in oxygen saturation, blood pressure and pulse rate during various endoscopic procedures and to find out the risk factors for these changes.
Observational study.
Department of Gastroenterology, Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan from June 2001 to December 2001 were included in the study.
Oxygen saturation, blood pressure and pulse were monitored during various endoscopic procedures using pulse oximeter. These changes were recorded from the start until 5 minutes after the procedure. The important variables which were evaluated in relation to these changes included age, gender, history of smoking, associated chronic obstructive airway disease (COAD), coronary artery disease (CAD), duration of procedure, elective versus emergency and diagnostic versus therapeutic procedures.
Base line mean oxygen saturation was 98.1+/-0.98 %. The saturation decreased to 93.5+/-4.8 % (p=0.002) during the procedures and returned to base line after the procedures. Mild to moderate hypoxia was found in 59 (20.2%) patients. Severe hypoxia was found in 32 (11.5%) patients. Of these 21(65.6%) patients were having history of COAD. No patient developed serious complications. The changes in blood pressure and pulse were not significant. The variables which reached statistical significance for desaturation were age>50 years, history of smoking, emergency procedures, therapeutic procedures and associated COAD. Diabetes mellitus (DM) and hypertension (HTN) alone, CAD and duration of procedures did not affect oxygen saturation.
Mild to moderate hypoxia is common during endoscopic procedures and of no serious consequence. Severe hypoxia is less common and is associated with underlying risk factors. Continuous monitoring is required in patients with age>50 years, history of smoking, emergency procedures, therapeutic procedures and history of COAD. Routine monitoring with pulse oximetry may not be required in patients with no risk factors.
确定各种内镜检查过程中血氧饱和度、血压和脉搏率的变化,并找出这些变化的危险因素。
观察性研究。
本研究纳入了2001年6月至2001年12月期间在巴基斯坦拉合尔谢赫·扎耶德研究生医学院胃肠病科进行的研究。
在各种内镜检查过程中,使用脉搏血氧仪监测血氧饱和度、血压和脉搏。从检查开始直至检查后5分钟记录这些变化。与这些变化相关评估的重要变量包括年龄、性别、吸烟史、相关慢性阻塞性气道疾病(COAD)、冠状动脉疾病(CAD)、检查持续时间、择期与急诊以及诊断性与治疗性检查。
基线平均血氧饱和度为98.1±0.98%。检查过程中饱和度降至93.5±4.8%(p = 0.002),检查后恢复至基线水平。59例(20.2%)患者出现轻度至中度低氧血症。32例(11.5%)患者出现严重低氧血症。其中21例(65.6%)患者有COAD病史。无患者发生严重并发症。血压和脉搏的变化不显著。导致血氧饱和度下降具有统计学意义的变量为年龄>50岁、吸烟史、急诊检查、治疗性检查以及相关COAD。单纯糖尿病(DM)和高血压(HTN)、CAD以及检查持续时间并未影响血氧饱和度。
内镜检查过程中轻度至中度低氧血症较为常见且无严重后果。严重低氧血症较少见且与潜在危险因素相关。年龄>50岁、有吸烟史、进行急诊检查、治疗性检查以及有COAD病史的患者需要持续监测。无危险因素的患者可能无需常规进行脉搏血氧饱和度监测。