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双侧突发性感音神经性听力损失作为原发灶不明的转移性腺癌的一种表现,在磁共振成像上酷似桥小脑角肿瘤。

Bilateral sudden sensorineural hearing loss as a presentation of metastatic adenocarcinoma of unknown primary mimicking cerebellopontine angle tumor on the magnetic resonance image.

作者信息

Jariengprasert Chanchai, Laothamatas Jiraporn, Janwityanujit Taweesak, Phudhichareonrat Suchart

机构信息

Department of Otolaryngology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Am J Otolaryngol. 2006 Mar-Apr;27(2):143-5. doi: 10.1016/j.amjoto.2005.07.019.

Abstract

This report presented a case of sudden profound bilateral sensorineural hearing loss with progressive facial diparesis in a 64-year-old woman. The magnetic resonance imaging (MRI) finding mimicked bilateral masses in the cerebellopontine angle (CPA) in an absence of clinical meningeal or parenchymal involvements at the first presentation. Surgical biopsy and histopathologic finding identified masses secondary to direct invasion of adenocarcinoma of gastrointestinal origin. Many investigations could not discover the primary site of the metastatic adenocarcinoma. Grave prognosis was observed in all cases reported including ours; the patient died 10 weeks after onset of symptoms.

摘要

本报告介绍了一名64岁女性突发双侧严重感音神经性听力损失并伴有进行性面部轻瘫的病例。磁共振成像(MRI)检查结果显示,在首次就诊时,双侧小脑桥脑角(CPA)有类似肿块,但无临床脑膜或实质受累表现。手术活检及组织病理学检查发现肿块是由胃肠道来源的腺癌直接侵犯所致。多项检查均未发现转移性腺癌的原发部位。包括我们的病例在内,所有报道的病例预后均较差;该患者在症状出现10周后死亡。

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