Tuomisto M T, Terho T, Korhonen I, Lappalainen R, Tuomisto T, Laippala P, Turjanmaa V
Department of Psychiatry, Tampere University Hospital, University of Tampere, FI-33014 Tampere, Finland.
Physiol Behav. 2006 Apr 15;87(4):650-8. doi: 10.1016/j.physbeh.2005.12.012. Epub 2006 Feb 28.
Several telecare systems for long-term monitoring of the well-being of patients at home have been developed as an aid in healthcare and to reduce hospitalization costs. Most of the systems have been designed to measure only one or two variables. Because well-being is a combination of both psychological and physiological wellness, there is a need to monitor several psychophysiological variables simultaneously in out-of-hospital conditions for a long period. To understand better the variability of patients' wellness-related variables in long-term recordings, the knowledge of the normal variation in health-related variables in healthy people is necessary. In our study, 14 healthy working middle-aged men were studied daily for 24 h and periods of 50 to 79 days. The variables measured were beat-to-beat heart rate, motor activity, blood pressure, body weight, and temperature. At night respiratory frequency, time of movements, amount of quiet sleep, and ballistocardiographic respiratory variation were also measured. Heart rate variability in the waking period was calculated later (standard deviation of the 5 min average of the successive normal to normal beat to beat intervals). Daily self-reported well-being, activities, and consumption of alcohol were monitored by keeping a behavioral diary. After normalizing the physiological data, the diurnal and weekly variability was calculated for each variable. In several variables the most notable diurnal and weekly variability was found between working time and free time. In conclusion, diurnal and weekly rhythms in several wellness-related physiological and psychological variables were identified, depending on working and free-time in healthy middle-aged men.
已经开发了几种用于长期监测居家患者健康状况的远程护理系统，以辅助医疗保健并降低住院成本。大多数系统仅设计用于测量一两个变量。由于健康是心理和生理健康的综合体现，因此需要在院外条件下长时间同时监测多个心理生理变量。为了更好地理解长期记录中患者健康相关变量的变异性，了解健康人群中与健康相关变量的正常变异情况是必要的。在我们的研究中，对14名健康的在职中年男性进行了为期50至79天、每天24小时的研究。测量的变量包括逐搏心率、运动活动、血压、体重和体温。夜间还测量了呼吸频率、运动时间、安静睡眠时间和心冲击图呼吸变异。随后计算清醒期的心率变异性（连续正常心跳间期5分钟平均值的标准差）。通过记录行为日记来监测每日自我报告的健康状况、活动和酒精摄入量。对生理数据进行归一化处理后，计算每个变量的昼夜和每周变异性。在几个变量中，工作时间和空闲时间之间的昼夜和每周变异性最为显著。总之，在健康中年男性中，根据工作和空闲时间，确定了几个与健康相关的生理和心理变量的昼夜和每周节律。
