Nakata S, Miki M, Okabe K, Mashimo T, Kobayashi M, Yamanaka H, Takahashi O, Onuki T
Department of Urology, Asama General Hospital.
Hinyokika Kiyo. 1991 May;37(5):507-14.
We reviewed 497 patients with male urethritis diagnosed between January, 1986 and March, 1989 at the Asama General Hospital. The incidence of gonococcal urethritis (GU) was 47.7%, and that of non-gonococcal urethritis (NGU) 52.3%. There was no difference in the age distribution between GU and NGU. Prostitutes were the most common source of the infection in both GU and NGU. Incubation periods were longer in NGU than in GU, statistically. Urethral discharge was the most common symptom. Purulent urethral discharge was seen more commonly than serous urethral discharge in GU. On the contrary, serous urethral discharge was more common in NGU. Penicillin-resistant gonococcus comprised 29.4% and mixed infection of the C. trachomatis existed 25.6% in GU. C. trachomatis was detected in 71.8% in NGU. In GU, new quinolones and penicillins were administered frequently. The effective rates 1 week after the administration were 80.6% and 83.3%, respectively. In NGU, new quinolones and minocycline were administered frequently. The effective rates were 70.4% and 85.3%, respectively. Ofloxacin (OFLX) showed the highest effective rate to NGU among the four new quinolones. The relapse rate for the two-week administration group was lower than that for the one-week-administration group, but the difference was not statistically significant.
我们回顾了1986年1月至1989年3月间在浅间综合医院诊断出的497例男性尿道炎患者。淋菌性尿道炎(GU)的发病率为47.7%,非淋菌性尿道炎(NGU)的发病率为52.3%。GU和NGU的年龄分布没有差异。妓女是GU和NGU中最常见的感染源。从统计学上看,NGU的潜伏期比GU长。尿道分泌物是最常见的症状。在GU中,脓性尿道分泌物比浆液性尿道分泌物更常见。相反,浆液性尿道分泌物在NGU中更常见。耐青霉素淋球菌占29.4%,GU中沙眼衣原体混合感染率为25.6%。NGU中沙眼衣原体检出率为71.8%。在GU中,新型喹诺酮类药物和青霉素类药物使用频繁。给药1周后的有效率分别为80.6%和83.3%。在NGU中,新型喹诺酮类药物和米诺环素使用频繁。有效率分别为70.4%和85.3%。在四种新型喹诺酮类药物中,氧氟沙星(OFLX)对NGU的有效率最高。两周给药组的复发率低于一周给药组,但差异无统计学意义。